1
Woolf Clifford, D Urso Donatella, Befort Katia, Costigan Michael: Nucleic acid and amino acid sequences involved in pain. The General Hospital Corporation, Bayer, Woolf Clifford, D Urso Donatella, Befort Katia, Costigan Michael, WILLIAMS Kathleen Madden, February 27, 2003: WO/2003/016475 (7 worldwide citation)

The present invention relates to nucleic acid sequences which are related to pain and which are differentially expressed during pain. The invention further relates to methods of identifying nucleic acid sequences which are differentially expressed during pain, microarrays comprising such differentia ...


2
Woolf Clifford J, Costigan Michael, Max Mitchell B, Belfer Inna, Atlas Steven J, Kingman Albert, Wu Tianxia, Goldman David: Diagnostic methods for pain sensitivity and chronicity and for tetrahydrobiopterin-related disorders. The General Hospital Corporation, National Institutes Of Health, Woolf Clifford J, Costigan Michael, Max Mitchell B, Belfer Inna, Atlas Steven J, Kingman Albert, Wu Tianxia, Goldman David, ELBING Karen L, June 14, 2007: WO/2007/067263 (1 worldwide citation)

Disclosed herein are methods for determining whether a subject possesses altered pain sensitivity an altered risk of developing acute or chronic pain, or diagnosing a tetrahydrobiopterin (BH4)-related disorder or a propensity thereto. These methods are based on the discovery of GCHl and KCNSl alleli ...


3
Woolf Clifford, D Urso Donatella, Costigan Michael: Nucleic acid and amino acid sequences involved in pain. The General Hospital Corporation, Woolf Clifford, D Urso Donatella, Costigan Michael, WILLIAMS Kathleen M, July 7, 2005: WO/2005/060667

The present invention relates to nucleic acid sequences which are related to pain and which are differentially expressed during pain. The invention further relates to methods of identifying nucleic acid sequences which are differentially expressed during pain, microarrays comprising such diffrential ...


4
Woolf Clifford J, Costigan Michael, Griffin Robert, Tegeder Irmgard: Methods for treating pain. The General Hospital Corporation, Woolf Clifford J, Costigan Michael, Griffin Robert, Tegeder Irmgard, ELBING Karen L, June 2, 2005: WO/2005/048926

The present invention features methods and compositions for preventing, reducing, or treating a traumatic, metabolic or toxic peripheral nerve lesion or pain including, for example, neuropathic pain, inflammatory and nociceptive pain by administering to a mammal in need thereof a compound that reduc ...