1
James E Shapland, Mark B Knudson, Jin Shimada: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 15, 1994: US05286254 (568 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


2
J Edward Shapland, Keith R Hildelbrand, Joel R Racchini, Jin Shimada, Mark B Knudson: Polymer matrix drug delivery apparatus. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt P A, September 15, 1998: US05807306 (452 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue using a catheter device including a polymer matrix containing a drug. The drug is actively transported from the polymer matrix to the internal body tissue using iontophoresis or phonophoresis. In addition, the ...


3
James E Shapland, Mark B Knudson, Jin Shimada: Phoretic balloon catheter with hydrogel coating. Cortrak Medical, Moore & Hansen, May 13, 1997: US05628730 (401 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


4
James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Drug delivery apparatus and method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, February 1, 1994: US05282785 (294 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall ...


5
Joel R Racchini, James E Shapland, Mark B Knudson, Jin Shimada, Keith R Hildebrand: Porous balloon for selective dilatation and drug delivery. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, October 17, 1995: US05458568 (288 worldwide citation)

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing t ...


6
James E Shapland, Keith R Hildebrand: Simultaneous cardiac pacing and local drug delivery method. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt PA, June 3, 1997: US05634899 (288 worldwide citation)

An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.


7
James E Shapland, Keith R Hildebrand: Simultaneous cardiac pacing and local drug delivery. Cortrak Medical, Merchant Gould Smith Edell Welter & Schmidt P A, February 2, 1999: US05865787 (228 worldwide citation)

An apparatus and method for delivering a drug selectively and locally to internal body tissue with a catheter using electric current/voltage controlled in conjunction with active pacing of cardiac activity.


8
James E Shapland, Keith R Hildebrandt, Mark B Knudson: Method for iontophoretically delivering drug adjacent to a heart. Cortrak Medical, Merchant Gould Smith Edell Welter & Schmidt, March 19, 1996: US05499971 (206 worldwide citation)

A drug delivery apparatus and method for iontophoretically delivering a drug locally to internal body tissue. The iontophoretic delivery apparatus and method include a current source producing a net flow of current in a desired direction with high frequency waveforms which enhance delivery and minim ...


9
James E Shapland, Mark B Knudson, Jin Shimada, Joel R Racchini: Simultaneous angioplasty and phoretic drug delivery. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt, March 12, 1996: US05498238 (196 worldwide citation)

A method of simultaneous angioplasty and drug delivery to a localized portion of coronary or peripheral arteries or any other type of body passage that has a stricture. The invention contemplates positioning a drug delivery device in a body passageway and then selectively introducing a selected drug ...


10
Joel R Racchini: Microporous catheter. CorTrak Medical, Merchant Gould Smith Edell Welter & Schmidt PA, October 29, 1996: US05569198 (141 worldwide citation)

An apparatus for delivering an agent to a treatment area. The apparatus includes a catheter that has a distal portion and a proximal portion. The catheter defines a lumen. A pressure regulator is in fluid communication with the lumen. A selectively inflatable member is also in fluid communication wi ...