1
Jacques Chevallet, Paul Priest, Keith Manica: Integrated blood treatment fluid module. Cobe Laboratories, Sheridan Ross & McIntosh, August 15, 1995: US05441636 (172 worldwide citation)

An integrated blood treatment fluid module is provided having particular multi-function application in the treatment of renal failure. The module comprises a support member, a blood treatment device mounted to the support member, and multiple fluid circuits, wherein a plurality of the fluid circuits ...


2
Lori A Truitt, Frank Corbin III, Donn D Lobdell, Douglas P Miller, Keith Manica, George J Eilers, Steven H Johnson, Lawrence L Leppert: Technique for extracorporeal treatment of blood. COBE Laboratories, Carol W Holland & Hart Burton, June 8, 1999: US05910252 (168 worldwide citation)

Blood from a patient is treated extracorporeally by any selected one of a plurality of predetermined treatments. Each of the treatments involves the flow of blood from the patient into a primary chamber of a filtration unit, past a semipermeable membrane located in the filtration unit which separate ...


3
John R Prybella, Terry D Boucher: Condition responsive pump control utilizing integrated, commanded, and sensed flowrate signals. Cobe Laboratories, January 3, 1989: US04795314 (149 worldwide citation)

A pump control apparatus including a variable speed pump controllable in response to a pump drive signal, a signal generator generating a commanded flowrate signal indicating desired flowrate of the pump, a flowrate sensor providing a sensed flowrate signal indicating sensed flowrate of the pump, an ...


4
Dennis Hlavinka: Tubing set apparatus and method for separation of fluid components. Cobe Laboratories, Finnegan Henderson Farrabow Garrett & Dunner L, April 25, 2000: US06053856 (135 worldwide citation)

An apparatus and method are provided for separating components of a fluid or particles. A separation vessel having a barrier dam is provided to initially separate an intermediate density components of a fluid, and a fluid chamber is provided to further separate these the intermediate density compone ...


5
Gary B Heath, William G Palsulich, Keith J Manica, Jack C Swan Jr: Apparatus for use with fluid flow transfer device. Cobe Laboratories, May 19, 1987: US04666598 (135 worldwide citation)

A fluid flow chamber cassette that can be mounted with either its front wall or rear wall against a supporting machine and has a flexible tube that extends from a sidewall and forms a loop that is symmetrical about a loop axis that is transverse to the side wall so that the loop will be acted upon b ...


6
Alfred P Mulzet: Continuous-loop centrifugal separator. Cobe Laboratories, November 24, 1987: US04708712 (131 worldwide citation)

Centrifuge apparatus for use in separating a heavy phase from a light phase in a rotating bowl, the apparatus comprising means defining a channel forming a continuous loop and having an inlet, a first outlet, and a dam portion spaced along the channel from the inlet and having an inner wall radius t ...


7
Dennis Hlavinka, Robert Langley, Linda Taylor, John C Walker: Apparatus for separating particles. Cobe Laboratories, Finnegan Henderson Farabow Garrett & Dunner L, October 7, 1997: US05674173 (118 worldwide citation)

A fluid chamber and method are disclosed for filtering or separating particles. The fluid chamber includes a wall extending between an inlet and outlet to form a fluid chamber interior. The interior converges from a position of maximum cross-sectional area toward the inlet. A groove or a step may be ...


8
Lori A Truitt, Douglas P Miller, Keith Manica: Automatic priming technique. COBE Laboratories, Carol W Holland & Hart Burton Esq, July 7, 1998: US05776345 (113 worldwide citation)

Blood from a patient is treated extracorporeally by any selected one of a plurality of predetermined treatments. Each of the treatments involves the flow of blood from the patient into a primary chamber of a filtration unit, past a semipermeable membrane located in the filtration unit which separate ...


9
David A Johnson, Douglas P Miller, Keith J Manica, William M Dormont, Christopher J Welsh, William R Mandel: Method and apparatus for ultrasonic detection of air bubbles. COBE Laboratories, Bruce R Winsor, March 7, 1995: US05394732 (105 worldwide citation)

Inclusions in a liquid flow, such as air bubbles in a blood flow, are detected by transmitting a signal through the fluid and receiving and interpreting the received signal based on the expected degree of attenuation for the liquid and the inclusions. The amplitude of the transmitted signal is autom ...


10
Terry R Wahl, Denise C Garrison, Chad C Steele, Timothy M Gordon, David W Hoard, Edward V Cruz: Apheresis blood processing method using pictorial displays. Cobe Laboratories, Sheridan Ross P C, August 5, 1997: US05653887 (103 worldwide citation)

An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of th ...