1
Karl F Mueller, Eduard K Kleiner: Polysiloxane hydrogels. Ciba Geigy Corporation, Luther A R Hall, January 23, 1979: US04136250 (513 worldwide citation)

A water-insoluble hydrophilic gel comprising (A) about 20 to about 90% by weight of a hydrophilic (a) polymer of identical or different water-soluble monoolefinic monomers, or (b) copolymer of said water-soluble monomers with 1 to 80% (of total monomers) of water-insoluble, identical or different mo ...


2
Ping I Lee: Method of producing annealed polyvinyl alcohol contact lens. Ciba Geigy Corporation, Michael W Glynn, Irving M Fishman, October 28, 1986: US04619793 (408 worldwide citation)

Optically clear soft contact lenses of aqueous swollen solid polyvinyl alcohol having a weight average molecular weight of at least 6,000, having been annealed under crystallinity promoting conditions to effectively increase the elastic modulus of the swollen lenses, and optionally subsequently cros ...


3
Jurg Zimmermann: Pyrimidine derivatives and processes for the preparation thereof. Ciba Geigy Corporation, Karen G Kaiser, May 28, 1996: US05521184 (344 worldwide citation)

There are described N-phenyl-2-pyrimidine-amine derivatives of formula I ##STR1## wherein R.sub.1 is 4-pyrazinyl, 1-methyl-1H-pyrrolyl, amino- or amino-lower alkyl-substituted phenyl wherein the amino group in each case is free, alkylated or acylated, 1H-indolyl or 1H-imidazolyl bonded at a five-mem ...


4
Christian Leumann: Bicyclic nucleosides, oligonucleotides, process for their preparation and intermediates. Ciba Geigy Corporation, Kevin T Mansfield, George R Dohmann, June 7, 1994: US05319080 (309 worldwide citation)

Compounds of the formula I in the form of the racemates or enantiomers thereof, ##STR1## in which R.sub.1 and R.sub.2 independently of one another are hydrogen or a protective group, and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for th ...


5
Christian Leumann: Bicyclic nucleosides, oligonucleotides, process for their preparation and intermediates. Ciba Geigy Corporation, George R Dohmann, February 28, 1995: US05393878 (302 worldwide citation)

Compounds of the formula I in the form of the racemates or enantiomers thereof, ##STR1## in which R.sub.1 and R.sub.2 independently of one another are hydrogen or a protective group, and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for th ...


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Kai C Su, J Richard Robertson: Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof. Ciba Geigy Corporation, Irving M Fishman, Michael W Glynn, April 26, 1988: US04740533 (233 worldwide citation)

Contact lenses which are optically clear, wettable, flexible, of high oxygen permeability and substantially non-swellable in the aqueous ocular environment of use, of a block copolymer containing polysiloxane and polyoxyalkylene oxide units are disclosed, as well as the preparation thereof and metho ...


8
Karl Heinz Altmann, Ren e Imwinkelried, Albert Eschenmoser: Carbocyclic nucleosides containing bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates. Ciba Geigy Corporation, Ronald J Campbell, Kevin T Mansfield, March 11, 1997: US05610300 (231 worldwide citation)

Compounds of the formulae I and Ia and their racemates ##STR1## in which A is --CH.sub.2 -- or --CH.sub.2 CH.sub.2 --, R.sub.1 is hydrogen or a protective group, R.sub.2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimi ...


9
Karl F Mueller: Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof. Ciba Geigy Corporation, Luther A R Hall, April 23, 1991: US05010141 (214 worldwide citation)

Vinyl unsaturated copolymers are described which are obtained in a two-step process and which consist of monomeric units A, B, C, D and E, copolymerized in a first step, and in a second step reacted with a reactive vinyl monomer M.sub.v, and in which A is a siloxane or fluorine containing vinyl mono ...


10
Winfried S Wels, Nancy E Hynes, Ina Maria Harweth, Bernd Groner, Norman Hardman, Markus Zwickl: Recombinant antibodies specific for a growth factor receptor. Ciba Geigy Corporation, James Scott Elmer, November 5, 1996: US05571894 (195 worldwide citation)

The invention concerns recombinant antibodies directed to the extracellular domain of the human growth factor receptor c-erbB-2 comprising a light chain variable domain and a heavy chain variable domain of a monoclonal antibody, monoclonal antibodies directed to c-erbB-2 themselves, a method of manu ...