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Lin Herbert Y, Babitt Jodie, Chung Raymond T, Samad Tarek A, Schneyer Alan L, Woolf Clifford: Use of modulatirs of compounds of tgf-beta superfamily to regulate hepcidin-mediated iron metabolism. The General Hospital Corporation, Lin Herbert Y, Babitt Jodie, Chung Raymond T, Samad Tarek A, Schneyer Alan L, Woolf Clifford, ELBING Karen L, August 24, 2006: WO/2006/088972 (34 worldwide citation)

The present invention provides new systems and strategies for the regulation of iron metabolism in mammals. In particular, methods of using agonists and antagonists of TGF-&bgr; superfamily members to modulate the expression or activity of hepcidin, a key regulator of iron metabolism, are described. ...


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Schreiber Stuart, Chung Raymond T, Peng Lee F, Kim Sun Suk, Matchacheep Sirinya, Porco Jr John A, Beeler Aaron B: Anti-viral compounds, compositions and methods. President And Fellows Of Harvard College, The General Hospital Corporation, Trustees Of Boston University, Schreiber Stuart, Chung Raymond T, Peng Lee F, Kim Sun Suk, Matchacheep Sirinya, Porco Jr John A, Beeler Aaron B, HUNTER BAKER C MD PHD JD, October 16, 2008: WO/2008/124571

The present invention is directed to compounds of formulae (I) and (II) and pharmaceutically acceptable forms thereof; pharmaceutical compositions thereof; and methods of treating a viral infection, such as a hepatitis C virus (HCV) infection, by administering to a subject diagnosed with or being su ...