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Chiesi Paolo: A device for dispensing metered amounts of aerosol for inhalation.. Chiesi Farma, December 27, 1989: EP0347779-A2 (63 worldwide citation)

The invention concerns an apparatus for the administration of drugs in form of metered aerosol, consisting of an expansion chamber (3) comprising two coaxial tubes (1, 2) freely slidable within one another and detachable. The external tube (1) has an open end (4) and a tapered end (5) on which the c ...


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Lewis David, Ganderton David, Meakin Brian, Brambilla Gaetano, Ferraris Alessandra: Stable pharmaceutical solution formulations for pressurised metered dose inhalers. Chiesi Farma, November 28, 2001: EP1157689-A1 (34 worldwide citation)

An aerosol solution composition for use in an aerosol inhaler comprises an active material, a propellant containing a hydrofluoroalkane, a cosolvent and optionally a low volatility component to increase the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuation of the inhaler. ...


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Chiesi Paolo, Panza Isabella, Ventura Paolo, Del Corno Marco, Varesco Mario: Device for mouth-inhaling aerosol medicaments.. Chiesi Farma, March 18, 1992: EP0475257-A1 (17 worldwide citation)

The invention provides a device for mouth-inhaling medicaments dispensed as aerosols by pressurized cans (16). The device is flat and compact in shape, comprises a seat for housing a can and defines an expansion chamber (3) into which the aerosol dispensed by the can, when operated, penetrates and e ...


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Chiesi Paolo, Pavesi Luciana: New pharmaceutical compositions for inhalation.. Chiesi Farma, October 7, 1987: EP0239798-A1 (17 worldwide citation)

A new excipient which may be used in the preparation of pharmaceutical compositions in the form of powders for inhalation, constituted by microgranules of a conglomerate of one or more solid water-soluble diluents and a lubricant.


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Ventura Paolo, Brambilla Gaetano, Garzia Rafaella, Lewis Andrew David, Ganderton David, Meakin Brian John: Pharmaceutical aerosol compositions. Chiesi Farma, December 23, 1998: GB2326334-A (15 worldwide citation)

A composition for use in an aerosol inhaler comprises an active material, a propellant containing a hydrofluoroalkane and a cosolvent. The composition further includes a low volatility component which is added to increase the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuat ...


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Chiesi Paolo, Pavesi Luciana: Aqueous pharmaceutical formulations of piroxicam monohydrate.. Chiesi Farma, April 30, 1986: EP0179430-A2 (15 worldwide citation)

Aqueous pharmaceutical compositions, containing as the active ingredient N-(2-pyridyl)-2-methyl-4-hydroxy-2H- 1,2-benzothiazine-3-carboxamide 1,1-dioxyde in the monohydrated form. The compositions of the invention are stable and do not undergo to crystal growth phenomena.


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Chiesi Paolo, Ventura Paolo, Panza Isabella: Device for the administration of powdered medicinal substances.. Chiesi Farma, October 16, 1991: EP0451745-A1 (15 worldwide citation)

This invention relates to a new inhaler for the local administration of powdered drugs to the respiratory tract. The apparatus consists of a nozzle (1) and a main body (2) which itself defines a storage chamber (8) for the medicinal substance, a dosing means (14,17) which supplies precisely measured ...


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Chiesi Paolo, Servadio Vittorino, Razzetti Roberta: Thiomethyl and sulfinylmethyl derivatives having gastric acid antisecretory activity, processes for the preparation thereof and pharmaceutical compositions containing them.. Chiesi Farma, February 1, 1989: EP0301422-A2 (8 worldwide citation)

Compounds of the formula Het-S(O)n-CH2-A (I) wherein Het is a substituted imidazolyl, purinyl, thieno-imidazolyl or imidazo-pyridyl group, n is 0 or 1, A is one of the following structures: and their physiologically acceptable salts have antiulcer and gastric acid antisecretory activity.


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Chiesi Paolo, Servadio Vittorino: 1,4:3,6-dianhydrosorbitol 2-mono-nitrate and 5-mononitrate esters, a process for the preparation thereof and pharmaceutical compositions therefrom.. Chiesi Farma, November 17, 1988: EP0290885-A2 (8 worldwide citation)

Isosorbide 2- and 5-mononitrate esters with aliphatic, aryl, or cynnamic acids or diacids, or with alkylcarbonyloxy substituents optionally containing an isosorbide 2- or 5-mononitrate group, are useful in human therapy.


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