1
Stéphane De Lombaert
BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M: INHIBITEURS OXADIAZOLE DE PRODUCTION DE LEUCOTRIÈNES, OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M, MORRIS Michael P, March 29, 2012: WO/2012/040137

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases an ...


2
Stéphane De Lombaert
CHEN Zhidong, DE LOMBAERT Stéphane, DINES Jonathon Alan, LIU Weimin, LO Ho Yin, LOKE Pui Leng: INHIBITEURS BENZIMIDAZOLES DE LA PRODUCTION DE LEUCOTRIÈNES, BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, CHEN Zhidong, DE LOMBAERT Stéphane, DINES Jonathon Alan, LIU Weimin, LO Ho Yin, LOKE Pui Leng, MORRIS Michael P, May 3, 2012: WO/2012/058254

The present invention relates to compounds of formula IA and IB and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various disea ...


3

4

5

6

7
Chen Zhidong, Cirillo Pier Francesco, Disalvo Darren, Liu Weimin, Marshall Daniel Richard, Wu Lifen, Young Erick Richard Roush: Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxylic acid amide compounds as ikk inhibitors. Boehringer Ingelheim Pharmaceuticals, Chen Zhidong, Cirillo Pier Francesco, Disalvo Darren, Liu Weimin, Marshall Daniel Richard, Wu Lifen, Young Erick Richard Roush, MORRIS Michael P, June 23, 2005: WO/2005/056562 (2 worldwide citation)

Disclosed are compounds of formula (I): wherein the variables R1, R2, R3 and Z are described herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases infla ...


8

9
BERRY Angela, CHEN Zhidong, DE LOMBAERT Stephane, EMMANUEL Michel Jose, LOKE Pui Leng, MAN Chuk Chui, MORWICK Tina Marie, TAKAHASHI Hidenori: INHIBITEURS BIARYLAMIDE DE PRODUCTION DE LEUKOTRIÈNES, BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, BERRY Angela, CHEN Zhidong, DE LOMBAERT Stephane, EMMANUEL Michel Jose, LOKE Pui Leng, MAN Chuk Chui, MORWICK Tina Marie, TAKAHASHI Hidenori, MORRIS Michael P, June 21, 2012: WO/2012/082817 (1 worldwide citation)

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, C, R1a, R1b, R2, R3, R4a and R4b are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in th ...


10
BALESTRA Michael, BURKE Jennifer, CHEN Zhidong, COGAN Derek, FADER Lee, GUO Xin, MCKIBBEN Bryan, MARSHALL Daniel Richard, NEMOTO Peter Allen, YU Hui: [fr] INHIBITEURS DE LALDOSTÉRONE SYNTHASE, [en] ALDOSTERONE SYNTHASE INHIBITORS. BOEHRINGER INGELHEIM INTERNATIONAL, BALESTRA Michael, BURKE Jennifer, CHEN Zhidong, COGAN Derek, FADER Lee, GUO Xin, MCKIBBEN Bryan, MARSHALL Daniel Richard, NEMOTO Peter Allen, YU Hui, MORRIS Michael P, November 6, 2014: WO/2014/179186 (1 worldwide citation)

[en] The present invention relates to compounds of formula (I): I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, W, Y, mand nare as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compoun ...