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Chen Yuanwei, O Connor Stephen James, Gunn David, Newcom Jason, Chen Jianqing, Yi Lin, Zhang Hai Jun, Hunyadi Laszlo Matyas, Natero Reina: Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity. Bayer Pharmaceuticals Corporation, Chen Yuanwei, O Connor Stephen James, Gunn David, Newcom Jason, Chen Jianqing, Yi Lin, Zhang Hai Jun, Hunyadi Laszlo Matyas, Natero Reina, GREENMAN Jeffrey M, July 15, 2004: WO/2004/058727 (45 worldwide citation)

This invention relates to substituted 3,5-dihydro-4H-imidazol-4-ones compounds which are useful in the treatment of obesity and obesity-related disorders, and as weight-loss and weight-control agents. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions com ...


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Wood Jill E, Chen Yuanwei, Hart Barry, Yi Lin, Chen Jianqing: Use of pyrimidine derivates for the manifacture of a medicament for the treatment of hyper-proliferative disorders. Bayer Pharmaceuticals Corporation, Wood Jill E, Chen Yuanwei, Hart Barry, Yi Lin, Chen Jianqing, GREENMAN Jeffrey M, May 13, 2004: WO/2004/039359 (43 worldwide citation)

A method of treating hyper-proliferative disorders comprising the administration to a patient in need thereof of an effective amount of a compound of Formula (I) wherein R is halo or CF3; n is 0 or 1; R1 is selected independently in each instance from the group consisting of halo, (C1-C3)alkoxy, and ...


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Scott William J, Dumas Jacques, Boyer Stephen, Lee Wendy, Chen Yuanwei, Phillips Barton, Verma Sharad, Chen Jianqing, Chen Zhi, Fan Jianmei, Raudenbush Brian, Redman Aniko, Yi Lin, Zhu Qingming: Novel cyanopyridine derivatives useful in the treatment of cancer and other disorders. Bayer Pharmaceuticals Corporation, Scott William J, Dumas Jacques, Boyer Stephen, Lee Wendy, Chen Yuanwei, Phillips Barton, Verma Sharad, Chen Jianqing, Chen Zhi, Fan Jianmei, Raudenbush Brian, Redman Aniko, Yi Lin, Zhu Qingming, TRAVERSO Richard J, September 16, 2004: WO/2004/078747 (36 worldwide citation)

This invention relates to novel diaryl ureas of Formula (I), pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper­proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.


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Dumas Jacques, Lee Wendy, Chen Yuanwei, Adnane Lila, Scott William J, Verma Sharad, Chen Jianging, Chen Zhi, Yi Lin: Substituted pyridine derivatives useful in the treatment of cancer and other disorders. Bayer Pharmaceuticals Corporation, Dumas Jacques, Lee Wendy, Chen Yuanwei, Adnane Lila, Scott William J, Verma Sharad, Chen Jianging, Chen Zhi, Yi Lin, TRAVERSO Richard J, September 16, 2004: WO/2004/078128 (23 worldwide citation)

This invention relates to novel diaryl ureas of formula I wherein A is phenyl, naphthyl, mono- or bi-cyclic heteroaryl, or a group of the formula B is phenyl, naphthyl, or pyridyl, L is a bridging group Q is: (1) C(S)NR4R5; (2) C(O)NR7-NR4R5; (3) tetrazolyl; (4) imidazolyl; (5) imidazoline-2-yl; (6) ...


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Chen Yuanwei, Cheng Huawei, Li Shengbin, Wu Yuelin, Feng Yan, Lv Binhua, Xu Baihua, Seed Brian, Hadd Michael J, Song Yanli, Du Jiyan, Wang Congna, Roberge Jacques Y: Benzylbenzene derivatives and methods of use. Theracos, Chen Yuanwei, Cheng Huawei, Li Shengbin, Wu Yuelin, Feng Yan, Lv Binhua, Xu Baihua, Seed Brian, Hadd Michael J, Song Yanli, Du Jiyan, Wang Congna, Roberge Jacques Y, KEZER William B, February 26, 2009: WO/2009/026537 (18 worldwide citation)

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other ther ...


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Chen Yuanwei, Feng Yan, Xu Baihua, Lv Binhua, Dong Jiajia, Seed Brian, Hadd Michael J: Glucose transport inhibitors and methods of use. Theracos, Chen Yuanwei, Feng Yan, Xu Baihua, Lv Binhua, Dong Jiajia, Seed Brian, Hadd Michael J, KEZER William B, December 6, 2007: WO/2007/140191 (17 worldwide citation)

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other ther ...


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