1
James W Bacus: Methods and apparatus for the quantitation of nuclear protein. Cell Analysis Systems, Fitch Even Tabin & Flannery, April 13, 1993: US05202931 (138 worldwide citation)

An image analysis system is used for the quantitation of nuclear proteins in cell populations. Particularly, the hormonal receptor content of fine needle aspirates of human breast carcinomas are evaluated. Estrogen or progesterone receptors are amplified and visualized in the specimen by a staining ...


2
James W Bacus: Method of and an apparatus for image analyses of biological specimens. Cell Analysis Systems, Fitch Even Tabin & Flannery, April 26, 1988: US04741043 (117 worldwide citation)

A user interactive system for dynamically testing and evaluating various cells, antigens, or other materials taken from the human body. More specifically, the DNA in specimen cells is analyzed and quantified by image analysis using pattern recognition techniques. The user is provided with a unique s ...


3
James W Bacus: Analysis method and apparatus for biological specimens. Cell Analysis Systems, Fitch Even Tabin & Flannery, May 21, 1991: US05018209 (76 worldwide citation)

A method and apparatus are provided for selecting and analyzing a subpopulation of cells or cell objects for a certain parameter such as DNA, estrogen, and then measuring the selected cells. The observer in real time views a field of cells and then gates for selection based on the morphological crit ...


4
James W Bacus, Ralph S Hernicz: Dual color camera microscope and methodology for cell staining and analysis. Cell Analysis Systems, Fitch Even Tabin & Flannery, July 28, 1992: US05134662 (66 worldwide citation)

A method and apparatus is disclosed for use in performing automated classification of cells and other microscopic specimens. The apparatus provides a compact, adjustable assembly that is operable to provide: an operator-apparatus interactive classification system for the cell analysis; alternative t ...


5
James W Bacus, Ralph S Hernicz: Dual color camera microscope and methodology for cell staining and analysis. Cell Analysis Systems, Fitch Even Tabin & Flannery, March 5, 1991: US04998284 (64 worldwide citation)

A method and apparatus is disclosed for use in performing automated classification of cells and other microscopic specimens. The apparatus provides a compact, adjustable assembly that is operable to provide: an operator-apparatus interactive classification system for the cell analysis; alternative t ...


6
James W Bacus: Method and apparatus for automated analysis of biological specimens. Cell Analysis Systems, Fitch Even Tabin & Flannery, August 10, 1993: US05235522 (57 worldwide citation)

An apparatus and method for analyzing the cell objects of a cell sample for the diagnosis and treatment of actual or suspected cancer is disclosed. An image of the cell sample is first digitized and morphological attributes, including area and DNA mass of the cell objects are automatically measured ...


7
James W Bacus: Methods and apparatus for the quantitation of nuclear proteins. Cell Analysis Systems, Fitch Even Tabin & Flannery, April 16, 1991: US05008185 (56 worldwide citation)

An image analysis system is used for the quantitation of nuclear proteins in cell populations. Particularly, the hormonal receptor content of fine needle aspirates of human breast carcinomas are evaluated. Estrogen or progesterone receptors are amplified and visualized in the specimen by a staining ...


8
James W Bacus, Robert J Marder: Methods for immunoploidy analysis. Cell Analysis Systems, Fitch Even Tabin & Flannery, January 25, 1994: US05281517 (53 worldwide citation)

A method and apparatus are provided for selecting and analyzing a subpopulation of cells or cell objects for a certain parameter such as DNA using image analysis means. The cells are first stained with an alkaline phosphatase technique including a monoclonal antibody specific to a protein in at leas ...


9
James W Bacus, Robert J Marder: Methods and apparatus for immunoploidy analysis. Cell Analysis Systems, Fitch Even Tabin & Flannery, May 14, 1991: US05016283 (46 worldwide citation)

A method and apparatus are provided for selecting and analyzing a subpopulation of cells or cell objects for a certain parameter such as DNA, estrogen, and then measuring the selected cells. The observer in real time views a field of cells and then gates for selection based on the morphological crit ...


10
James W Bacus, Sarah S Bacus: Method and apparatus for determining the amount of oncogene protein product in a cell sample. Cell Analysis Systems, Fitch Even Tabin & Flannery, October 12, 1993: US05252487 (45 worldwide citation)

An apparatus and method for determining an amount of oncogene protein product copies in a cell includes an optical conversion module for measuring an amount of optically enhanced DNA in a cell sample. A subsystem for measuring an amount of an optically enhanced oncogene protein product protein produ ...