1
KUSLICH CHRISTINE: Methods and systems of using exosomes for determining phenotypes. CARIS MPI, Skubatch Maya, May 20, 2010: WO/2010/056337 (17 worldwide citation)

Exosomes can be used for detecting biomarkers for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, for example, the stage or progression of a disease. Cell-of-origin exosomes can be used in profiling of physiological states or determining phen ...


2
Michael Klass, Christine Kuslich, George Poste: Methods for assessing RNA patterns. Caris MPI, Wilson Sonsini Goodrich & Rosati, February 15, 2011: US07888035 (15 worldwide citation)

Methods and compositions for the characterizing of cancers by assessing RNA levels, such as determining an RNA pattern, are provided herein. The diagnosis, prognosis, monitoring and treatment or a cancer can be determined by detecting one or more RNAs, such as microRNAs.


3
Daniel D Von Hoff, Robert J Penny: System and method for determining individualized medical intervention for a disease state. Caris MPI, Ramin Akhavan, December 16, 2014: US08914239 (9 worldwide citation)

A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from the patient, determining whether any molecular findings including one or more genes, one or more gene ...


4
Daniel D Von Hoff, Robert Penny: System and method for determining individualized medical intervention for a disease state. Caris MPI, Ramin Akhavan, April 15, 2014: US08700335 (8 worldwide citation)

A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from the patient, determining whether any molecular findings including one or more genes, one or more gene ...


5
Daniel D Von Hoff, Robert J Penny: System and method for determining individualized medical intervention for a disease state. Caris MPI, Ramin Akhavan, September 9, 2014: US08831890 (8 worldwide citation)

A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from the patient, determining whether any molecular findings including one or more genes, one or more gene ...


6
VON HOFF DANIEL D: Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type. CARIS MPI, Mah Angle S, April 22, 2010: WO/2010/045318 (8 worldwide citation)

Provided herein are methods and systems for identifying a therapeutic for an individual, such as a therapeutic not previously identified for treating the individual. The therapeutic can be identified by molecular profiling, such as determining the biomarker patterns or signature sets of a biological ...


7
DANENBERG Kathleen, BASU Gargi, ARGUELLO David: PROFILAGE MOLÉCULAIRE POUR LE CANCER, MOLECULAR PROFILING FOR CANCER. CARIS MPI, DANENBERG Kathleen, BASU Gargi, ARGUELLO David, AKHAVAN Ramin, December 13, 2012: WO/2012/170715 (7 worldwide citation)

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a trea ...


8
ALARCON Arlet, ARGUELLO David, BASU Gargi, KEMKES Ariane, FELDMAN Rebecca A, LOESCH David M: PROFILAGE MOLÉCULAIRE POUR LE CANCER, MOLECULAR PROFILING FOR CANCER. CARIS MPI, ALARCON Arlet, ARGUELLO David, BASU Gargi, KEMKES Ariane, FELDMAN Rebecca A, LOESCH David M, AKHAVAN Ramin, July 5, 2012: WO/2012/092336 (6 worldwide citation)

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a trea ...


9
Daniel D Von Hoff, David M Loesch, Arlet Alarcon, Robert J Penny, Alan Wright, Matthew J McGinniss, Ryan P Bender, Traci Pawlowski: Molecular profiling of tumors. Caris MPI, Ramin Akhavan, June 23, 2015: US09064045 (5 worldwide citation)

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a trea ...


10
Daniel D Von Hoff, David M Loesch, Arlet Alarcon, Robert J Penny, Alan Wright, Matthew J McGinniss, Ryan P Bender, Traci Pawlowski: Molecular profiling of tumors. Caris MPI, Ramin Akhavan, June 9, 2015: US09053224 (5 worldwide citation)

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a trea ...