1
Hugh P Bennetto, Gerard M Delaney, Jeremy R Mason, Christopher F Thurston, John L Stirling, David R DeKeyzer: Immobilized enzyme electrodes. Cambridge Life Sciences, St Onge Steward Johnston & Reens, November 13, 1990: US04970145 (418 worldwide citation)

Enzyme electrodes are disclosed which are capable of responding amperometrically to the catalytic activity of the enzyme in the presence of its respective substrate and comprising the enzyme immobilized or adsorbed onto the surface of an electrically conductive support member which consists of or co ...


2
William H Mullen: Enzyme electrodes and improvements in the manufacture thereof. Cambridge Life Sciences, St Onge Steward Johnston & Reens, November 3, 1992: US05160418 (286 worldwide citation)

Enzyme electrodes are disclosed consisting essentially of a uniform homogeneous layer of a finely divided platinum group metal or oxide, preferably preadsorbed onto the surface of an activated carbon or grapite powder, and deposited from suspension upon the surface of an electrically conductive subs ...


3
Dale Athey, Calum J McNeil, Ronald D Armstrong, William Henry Mullen: Sensors based on polymer transformation. Cambridge Life Sciences, Jacobson Price Holman & Stern PLLC, December 8, 1998: US05846744 (249 worldwide citation)

A sensor format is based on impedance analysis of polymer coatings of electrodes. A detectable signal is produced by the effect of a reactive or catalytic species at or very near the polymer coated electrode. The reactive or catalytic species directly or indirectly effects a reaction with the polyme ...


4
Skelly Peter: Multilayer enzyme electrode membrane and method of making same. Cambridge Life Sciences, May 24, 1989: GB2209836-A (43 worldwide citation)

A multilayer enzyme membrane for use in the polarographic detection of an enzyme substrate in a sample in the presence of a plurality of potentially interfering species. The membrane consists of a multilayer base (1a, 1b, 1c) supporting an immobilised enzyme-containing layer (2) and optionally cover ...


5
Lowe Christopher Robin: Conductimetric bioassay techniques.. Cambridge Life Sciences, October 10, 1984: EP0121385-A1 (41 worldwide citation)

The application discloses a novel method and device for carrying out conductimetric bioassays of a given analyte in a liquid sample. For this purpose a probe is dipped into the sample comprising an insulating support (30) having mounted on its surface a porous membrane (56) onto which has been immob ...


6
Andrew J Russell, Colin Calvert: Plate reader. Cambridge Life Sciences, St Onge Steward Johnston & Reens, March 7, 1989: US04810096 (40 worldwide citation)

A small, compact plate reader is disclosed for microtitre plates. The reader comprises a totally enclosed housing (19), means e.g. a drawer (2) for receiving and inserting into the housing a microtitre plate (7) which is received into the housing between a light source and a photodetector positioned ...


7
Bennetto Hugh Peter, Delaney Gerard Michael, Mason Jeremy Richard, Thurston Christopher Frank, Stirling John Laing, de Keyzer David Robert: Immobilized enzyme electrodes.. Cambridge Life Sciences, December 2, 1987: EP0247850-A1 (32 worldwide citation)

Enzyme electrodes are disclosed which are capable of responding amperometrically to the catalytic activity of the enzyme in the presence of its respective substrate and comprising the enzyme immobilised or adsorbed onto the surface of an electrically conductive support member which consists of or co ...


8
William H Mullen: Immobilized enzyme electrodes. Cambridge Life Sciences, St Onge Steward Johnston & Reens, July 27, 1993: US05231028 (19 worldwide citation)

Enzyme electrodes are described which are of reduced sensitivity to alcohol. The electrodes comprise a porous resin-bonded layer of powdered carbon or graphite, onto which the enzyme is immobilized, that layer containing either finely divided platinum oxide, or finely divided platinum the surface of ...


9
Skelly Peter: Enzyme electrode membrane and method of making same. Cambridge Life Sciences, March 16, 1988: GB2194843-A (15 worldwide citation)

An enzyme electrode membrane is disclosed comprising an immobilised enzyme containing layer 2 supported on a polymeric base comprising a layer 1 of alkoxy- substituted polyamide, preferably a spun cast layer of methoxynylon with a thickness in the range 0.5 to 1 micron. Additional base layers may be ...


10
Mcneil Calum, Hager Hans J, Mullen William, Wah On Ho: Electrochemical detection of specific binding species. Cambridge Life Sciences, October 5, 1994: GB2276724-A (12 worldwide citation)

The presence of an analyte in a sample, said analyte being a member of a specific being pair consisting of a ligand and an anti-ligand, is detected through the electrical signal produced by a chemical species with peroxidase activity which during the course of the assay becomes immobilised at or nea ...