Richard C Hevey, Mark K Malmros: Methods for the detection and determination of ligands. Calbiochem Behring, Natalie Jensen, October 14, 1980: US04228237 (117 worldwide citation)

A method for determining the presence of a ligand in a liquid medium which utilizes enzyme labeled avidin and biotin labeled reagent in a specific binding process wherein the ligand to be detected is contacted with an insoluble phase containing specific binding substance for the ligand. Various prot ...

Richard C Hevey, Mark K Malmros, Wayne W Petko: Method for terminating a peroxidase catalyzed reaction. Calbiochem Behring, Natalie Jensen, November 18, 1980: US04234680 (9 worldwide citation)

Addition of a low concentration of an alkali metal metabisulfite completely stops color development in a peroxidase-labeled immunoassay wherein the peroxidase catalyzed reaction comprises oxidation of an achromatic substrate to the corresponding chromatic product in the presence of a peroxide.

William Drell, John K Pollard Jr: Process of mitigating cholelithiasis. Calbiochem Behring, Natalie Jensen, August 8, 1978: US04105794 (2 worldwide citation)

Therapeutic composition useful for mitigating cholelithiasis in humans comprising 3-hydroxy-3-methylglutaric acid, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable non-toxic carrier.

Andre H Yavrouian: 3-Hydroxy-3-methylglutaric acid monoamide and derivatives thereof. Calbiochem Behring, Natalie Jensen, June 17, 1980: US04208204 (1 worldwide citation)

Disclosed as novel compounds are 3-hydroxy-3-methylglutaric acid monoamide and the lower alkyl esters and salts thereof, 3-hydroxy-3-methylglutaramide mononitrile and 3-hydroxy-3-methylglutaramide. 3-Hydroxy-3-methylglutaric acid monoamide and derivatives thereof exhibit anti-germination and anti-gr ...

John K Pollard Jr: Reagent system and method for assaying peptidase enzymes. Calbiochem Behring, Natalie Jensen, April 7, 1981: US04260681 (1 worldwide citation)

A reagent system for assaying a biological specimen for a peptidase enzyme comprising a peptide substrate in which the C-terminal amino acid is dehydroalanine, the enzyme lactate dehydrogenase, the reduced coenzyme nicotinamide adenine dinucleotide and a buffer material.

Arthur S Spangler deceased: Topical treatment of skin diseases. Calbiochem Behring, Natalie Jensen, January 9, 1979: US04133893 (1 worldwide citation)

A topical preparation for the treatment of skin diseases such as acne vulgaris, acne rosacea, psoriasis and herpes simplex which comprises 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane and a pharmaceutically acceptable carrier or diluent.

Mueller Hiltrud S, Lukes James J, Rao Parinam S: Epreuve differentielle des isoenzymes de la creatine phosphokinase, Differential assay of creatine phosphokinase isoenzymes. Calbiochem Behring, August 21, 1979: CA1060765

Abstract of the Disclosure A process for the determination of creatinephosphokinase MB-isoenzyme (CPK-MB) level inserum in which CPK is determined before and after MB-activation with 1,4-dimercapto-2,3-dihydroxybutane or 2-mercaptoethanol, preferably in anassay system using the ATP/ADP conversion. T ...

Bucolo Giovanni: Dosage enzymatique de lethanol, Enzymatic ethanol assay. Calbiochem Behring, January 9, 1979: CA1045961

Abstract of the Disclosure A composition useful for determining the ethanol content of body fluids consisting essentially of alcohol dehydrogenase, nicotinamide adenine dinucleotide, a buffer acetaldehyde/trapping agent and an acid.