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Andrews Steven W, Seiwert Scott, Beigelman Leonid, Blatt Lawrence, Buckman Brad: Novel peptide inhibitors of hepatitis c virus replication. Intermune, Array Biopharma, Andrews Steven W, Seiwert Scott, Beigelman Leonid, Blatt Lawrence, Buckman Brad, HART Daniel, November 20, 2008: WO/2008/141227 (54 worldwide citation)

The embodiments provide compounds of the general Formula (I), as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments provide compounds of the general Formula (II), as well as compositions, including pharmaceutical compositions, comprising a sub ...


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BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: Nouveaux inhibiteurs de la réplication du virus de lhépatite c, Novel inhibitors of hepatitis c virus replication. Intermune, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, HART Daniel, November 24, 2011: WO/2011/146401 (36 worldwide citation)

The embodiments provide compounds of the general Formulae (VI), (VII), (VIII), (IX), (X), (XI), (XII), (XIII), (XIV), and (XV) as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treati ...


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Seiwert Scott, Beigelman Leonid, Buckman Brad, Stoycheva Antitsa Dimitrova, Porter Steven B, Bradford Williamson Ziegler, Serebryany Vladimir: Novel macrocyclic inhibitors of hepatitis c virus replication. Intermune, Seiwert Scott, Beigelman Leonid, Buckman Brad, Stoycheva Antitsa Dimitrova, Porter Steven B, Bradford Williamson Ziegler, Serebryany Vladimir, Mallon Joseph J, November 26, 2009: WO/2009/142842 (25 worldwide citation)

The embodiments provide compounds of the general Formulae I, II, EI, IV, V, VI, VII, and X, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection an ...


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BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: NOUVEAUX INHIBITEURS DE LA RÉPLICATION DU VIRUS DE LHÉPATITE C, NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, MALLON Joseph J, June 28, 2012: WO/2012/087976 (16 worldwide citation)

The embodiments provide compounds of the general Formulae XV, XVI, XVII and XVIII as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods ...


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BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott: PEPTIDES ANTIVIRAUX THÉRAPEUTIQUES, THERAPEUTIC ANTIVIRAL PEPTIDES. INTERMUNE, BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott, ARNO Thomas R, April 12, 2012: WO/2012/047764 (11 worldwide citation)

The invention relates to compounds of Formula (I) (in which the variables are defined as herein) and compositions, including pharmaceutical compositions, thereof. The invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liv ...


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Bryant Judi, Buckman Brad, Islam Imadul, Mohan Raju, Morrissey Michael, Wei Guo Ping, Xu Wei, Yuan Shendong: 2-aminocarbonyl-quinoline compounds as platelet adenosine diphosphate receptor antagonists. Schering Aktiengesellschaft, Bryant Judi, Buckman Brad, Islam Imadul, Mohan Raju, Morrissey Michael, Wei Guo Ping, Xu Wei, Yuan Shendong, HERMENAU Ronald S, June 24, 2004: WO/2004/052366 (10 worldwide citation)

Compounds of formula (I), where m, n, R1, R2, R3, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, methods of using these compounds as antithrombotic agents and processes for synthesizing these compoun ...


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Buckman Brad O, Wang Guangyi, Beigelman Leonid, Stoycheva Antitsa Dimitrova: Novel inhibitors of hepatitis c virus replication. Intermune, Buckman Brad O, Wang Guangyi, Beigelman Leonid, Stoycheva Antitsa Dimitrova, MALLON Joseph J, November 5, 2009: WO/2009/134616 (10 worldwide citation)

The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibr ...


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BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D: INHIBITEURS PROLINE SUBSTITUÉE DE RÉPLICATION DU VIRUS DE LHÉPATITE C, SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, NICHOLAS John B, SEREBRYANY Vladimir, SEIWERT Scott D, MILLER Kimberly J, March 29, 2012: WO/2012/040242 (10 worldwide citation)

The embodiments provide compounds of the general Formulae I, la, II,IIa,III, IIIa, Illb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods ...


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BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott: NOUVEAUX INHIBITEURS MACROCYCLIQUES DE LA RÉPLICATION DU VIRUS DE LHÉPATITE C, NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION. INTERMUNE, BUCKMAN Brad, SEREBRYANY Vladimir, NICHOLAS John B, SEIWERT Scott, HART Daniel, April 26, 2012: WO/2012/054874 (9 worldwide citation)

The embodiments provide compounds of the general Formulae I, la, II, Ila, IIΙ, IIIa, IV, IVa, V, Va, VI and VIa, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis ...