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Natesan Murugesan: Substituted biphenyl isoxazole sulfonamides. Bristol Myers Squibb Company, Suzanne E Babajko, March 18, 1997: US05612359 (196 worldwide citation)

Compounds of the formula ##STR1## inhibit the activity of endothelin. The symbols are defined as follows: R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each directly bonded to a ring carbon and are each independently


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Ingegerg Hellstrom, Karl Erik Hellstrom, Kim Folger Bruce, George J Schreiber: Antibody conjugates reactive with human carcinomas. Bristol Myers Squibb Company, Merchant Gould Smith Welter and Schmidt, February 9, 1999: US05869045 (156 worldwide citation)

The present invention relates to novel antibodies, antibody fragments and antibody conjugates and single-chain immunotoxins reactive with human carcinoma cells. More particularly, the antibodies, conjugates and single-chain immunotoxins of the invention include: a murine monoclonal antibody, BR96; a ...


3
John N Insall, Giles R Scuderi, Pascal Poilvache, Robert A Hodorek, David J Krueger: Apparatus and method for knee implantation. Bristol Myers Squibb Company, Cary R Reeves, November 3, 1998: US05830216 (155 worldwide citation)

A set of instruments and a surgical technique facilitate precise orientation of the femoral implant. Precision is aided by decoupling the determination of A/P placement, valgus angle, and external rotation into three discrete steps. In this way, a surgeon's full concentration can be directed to each ...


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Peter C Miller, Joseph Fucci: Pre-loaded suture anchor with rigid extension. Bristol Myers Squibb Company, Gene Warzecha, January 13, 1998: US05707394 (142 worldwide citation)

A method and apparatus for facilitating use of a threaded suture anchor in combination with a reusable cannulated anchor driver. The device enables a suture anchor to be preassembled with a suture so that a user need not assemble a suture anchor with suture immediately prior to use. The preassembled ...


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Lisa K Schroder, David A Mann, G Kris Kumar, Steven C Kitch, Paul F Hickey, Timothy K Doolin, Philip H Cripe, Kim C Bertin: Orthopaedic positioning apparatus. Bristol Myers Squibb Company, Margaret L Geringer, September 14, 1999: US05951564 (134 worldwide citation)

The invention is directed to an orthopaedic apparatus 24, 80, 380, 480, 580 for positioning an implant 22, 322, 422 relative to an end of a bone. The implant has at least one extractor opening 30, 330, 430 and a shoulder 26, 326, 426 with a slot therein. The positioning apparatus includes a shaft 32 ...


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William G Hubbard: Soft tissue augmentation material. Bristol Myers Squibb Company, Theodore R Furman Jr, John M Kilcoyne, Stuart E Krieger, July 13, 1999: US05922025 (133 worldwide citation)

A permanent, biocompatible material for soft tissue augmentation. The biocompatible material comprises a matrix of smooth, round, finely divided, substantially spherical particles of a biocompatible ceramic material, close to or in contact with each other, which provide a scaffold or lattice for aut ...


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Mcphee Fiona, Campbell Jeffrey Allen, Li Wenying, D Andrea Stanley, Zheng Zhizhen Barbara, Good Andrew Charles, Carini David J, Johnson Barry L, Scola Paul Michael: Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus. Bristol Myers Squibb Company, Mcphee Fiona, Campbell Jeffrey Allen, Li Wenying, D Andrea Stanley, Zheng Zhizhen Barbara, Good Andrew Charles, Carini David J, Johnson Barry L, Scola Paul Michael, VOLLES Warren K, November 4, 2004: WO/2004/094452 (132 worldwide citation)

Macrocyclic isoquinoline are disclosed having the general formula: A compound of formula 1: wherein R1 to R9, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.


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Peter R Carter, Gary T Hamman, Kenneth S Jackson, Mari S Truman: Wrist fusion plate. Bristol Myers Squibb Company, Margaret L Geringer, December 29, 1998: US05853413 (124 worldwide citation)

The invention is directed to a wrist fusion plate 10 configured to extend over a carpus area and position at least one metacarpal relative to a radius. The wrist fusion plate includes a saddle portion 36 which is placed over the carpus area. A proximal end 38 extending from the saddle portion and at ...