Peter D Senter, Mark G Saulnier, Joseph P Brown, David E Kerr: Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells. Bristol Myers Company, Deborah J Barnett, December 4, 1990: US04975278 (294 worldwide citation)

This invention relates to a novel method for the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and the additional administration of a prodrug that is converted at the tumor site, in the presence of the an ...

Maxwell Gordon, Irwin J Pachter: Prevention of analgesic abuse. Bristol Myers Company, Richard R Lloyd, July 3, 1984: US04457933 (186 worldwide citation)

This invention concerns a method for decreasing both the oral and parenteral abuse potential of strong analgetic agents such as oxycodone, propoxyphene and pentazocine by combining an analgesic dose of the analgetic agents with naloxone in specific, relatively narrow ranges. Oxycodone-naloxone compo ...

Irwin J Pachter, Maxwell Gordon: Analgetic compositions. Bristol Myers Company, Robert E Havranek, June 29, 1976: US03966940 (101 worldwide citation)

Orally effective, analgetic compositions have been developed which are useful in the prevention of drug abuse because upon parenteral administration, they do not produce analgesia, euphoria, or physical dependence. Such compositions comprise an orally active, strong analgetic in oral dosage form and ...

David W Smith, Joseph P Yevich: Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives. Bristol Myers Company, Richard P Ryan, Robert H Uloth, May 20, 1986: US04590196 (92 worldwide citation)

A series of non-opiate analgesics of Formula I ##STR1## wherein R.sup.1 is hydrogen, alkyl, aralkyl, or aryloxyalkyl; R.sup.2 is alkyl or hydrogen; and R.sup.3 and R.sup.4 are independently selected from hydrogen, alkyl, acyloxy, alkoxy, alkylthio, halogen, hydroxyl, or trifluoromethyl; or a pharmac ...

Albert A Ricci: Shelf organizer. Bristol Myers Company, Gabriel P Katona, July 17, 1984: US04460096 (83 worldwide citation)

A variable shelf organizer adapted to being assembled to provide shelf organizers of various sizes. The elements are constructed so that portions of them may be cut or broken away to adjust the length and/or width thereof and so that the parts interlock to give product troughs of various lengths and ...

Pachter Irwin J, Gordon Maxwell: Method of treating drug addicts. Bristol Myers Company, Magee Jr James, April 22, 1975: US3879555 (81 worldwide citation)

A new and novel orally effective, analgetic composition has been found which, upon parenteral administration, does not produce analgesia, euphoria or physical dependence, said composition comprising an orally inactive dose of 1-N-cyclopropylmethyl-7,8-dihydro-14-hydroxynormorphinone (I) and an orall ...

Ralph H Thomas: Fluid unit dispensing device. Bristol Myers Company, Irving Holtzman, George A Mentis, February 3, 1981: US04248227 (76 worldwide citation)

A flexible unit dispensing device for a fluid comprising a squeezable hollow bulb portion and a cylindrical nozzle. The internal diameter of the nozzle is no smaller than 0.120 inches and the length of nozzle being such as to reach to the area of the rectal columns when the device is inserted in the ...

John C Godfrey: Flushable urinary catheter. Bristol Myers Company, Roylance Abrams Berdo & Farley, October 14, 1980: US04227533 (72 worldwide citation)

A urinary catheter comprising an elongated hollow tube having a proximal end, a distal end, a drainage opening in the distal end and a liquid drainage lumen extending from the opening to the proximal end. A valve is located in the lumen near the distal end. Under normal conditions, the valve is open ...

Taras Durbak, Ara Nersesian: Suspension composition of benzocaine. Bristol Myers Company, Irving Holtzman, George A Mentis, December 23, 1980: US04241048 (71 worldwide citation)

A composition containing a therapeutically effective amount of powdered benzocaine suspended in an essentially anhydrous carrier and further containing a copolymer of a vinylpyrrolidone and an alpha-olefin as a crystal growth suppressing agent.

Navin Geria: Antiperspirant stick composition. Bristol Myers Company, Irving Holtzman, George A Mentis, October 21, 1980: US04229432 (71 worldwide citation)

An antiperspirant stick composition in which the antiperspirant material is maintained substantially homogeneously distributed throughout the stick by virtue of the presence of certain waxy materials.

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