1
Wong Chi Huey, Brik Ashraf, Yang Yu Ying, Ficht Simon, Payne Richard: Method of preparing glycopeptides. The Scripps Research Institute, Wong Chi Huey, Brik Ashraf, Yang Yu Ying, Ficht Simon, Payne Richard, STEFFEY Charles E, October 4, 2007: WO/2007/111952 (17 worldwide citation)

A method is provided for the synthesis of glycopeptides using a sugar assisted ligation strategy, wherein an N-terminal peptide portion in the form of a thioester is coupled with a C-terminal peptide portion bearing a carbohydrate moiety comprising a thiol group.


2
BRIK Ashraf, KUMAR Ajish, ERLICH Leslie, SPASSER Liat: Synthèse expéditive de conjugués peptidiques ubiquitinés, An expeditious synthesis of ubiquitinated peptide conjugates. Ben Gurion University Of The Negev Research And Development Authority, BRIK Ashraf, KUMAR Ajish, ERLICH Leslie, SPASSER Liat, Pyernik Rutman, December 8, 2011: WO/2011/151826

The present invention discloses a process for preparing ubiquinated peptide conjugates comprising a ubiquitin peptide residue UR attached at its C-terminus to a substrate peptide via a native isopeptide bond, this process comprising combining Native Chemical Ligation (NCL) and solid phase peptide sy ...