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Stéphane De Lombaert
DE LOMBAERT Stéphane, LIU Weimin, LO Ho Yin, NEMOTO Peter Allen: INHIBITEURS BENZIMIDAZOLE DE PRODUCTION DE LEUCOTRIÈNES, BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, DE LOMBAERT Stéphane, LIU Weimin, LO Ho Yin, NEMOTO Peter Allen, MORRIS Michael P, May 10, 2012: WO/2012/061169 (1 worldwide citation)

The present invention relates to compounds of formula (IA), (IB) and (IC) and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of var ...


2
Stéphane De Lombaert
Stéphane De Lombaert, Michel Jose Emmanuel: Chymase inhibitors. Boehringer Ingelheim International, Michael P Morris, Anthony P Bottino, Usha R Patel, June 5, 2012: US08193214

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.


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Stéphane De Lombaert
BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M: INHIBITEURS OXADIAZOLE DE PRODUCTION DE LEUCOTRIÈNES, OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, BARTOLOZZI Alessandra, BOSANAC Todd, CHEN Zhidong, DE LOMBAERT Stéphane, HUBER John D, LIU Weimin, LO Ho Yin, LOKE Pui Leng, RIETHER Doris, TYE Heather, WU Lifen, ZINDELL Renee M, MORRIS Michael P, March 29, 2012: WO/2012/040137

The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases an ...


4
Stéphane De Lombaert
CHEN Zhidong, DE LOMBAERT Stéphane, DINES Jonathon Alan, LIU Weimin, LO Ho Yin, LOKE Pui Leng: INHIBITEURS BENZIMIDAZOLES DE LA PRODUCTION DE LEUCOTRIÈNES, BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, CHEN Zhidong, DE LOMBAERT Stéphane, DINES Jonathon Alan, LIU Weimin, LO Ho Yin, LOKE Pui Leng, MORRIS Michael P, May 3, 2012: WO/2012/058254

The present invention relates to compounds of formula IA and IB and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various disea ...


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Stéphane De Lombaert
Stéphane De Lombaert, Michel Jose Emmanuel: Chymase Inhibitors. Boehringer Ingelheim International, Michael P Morris, Boehringer Ingelheim Usa Corporation, February 4, 2010: US20100029637-A1

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.


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David T Curiel, Max L Birnstiel, Matthew Cotten, Ernst Wagner, Kurt Zatloukal, Christian Plank, Berndt Oberhauser, Walter G M Schmidt: Composition for introducing nucleic acid complexes into higher eucaryotic cells. Boehringer Ingelheim International, Genentech, Sterne Kessler Goldstein & Fox P L L C, August 20, 1996: US05547932 (198 worldwide citation)

A composition for the transfection of higher eucaryotic cells, comprising complexes of nucleic acid, a substance having an affinity for nucleic acid and optionally an internalizing factor, contains an endosomolytic agent, e.g. a virus or virus component, which may be conjugated. The endosomolytic ag ...


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David T Curiel, Ping chuan Hu, Max L Birnstiel, Matthew Cotten, Ernst Wagner: Conjugates for introducing nucleic acid into higher eucaryotic cells. Boehringer Ingelheim International, Genentech, University of North Carolina at Chapel Hill, Sterne Kessler Goldstein & Fox, May 28, 1996: US05521291 (176 worldwide citation)

Conjugates in which a virus is bound via an antibody to a substance having an affinity for nucleic acid, for transporting gene constructs into higher eucaryotic cells. Complexes of the conjugates and nucleic acid are internalized in the cell, whilst the virus as part of the complex brings about the ...


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Frank Bartels, Wulf Bachtler, Stephen T Dunne, Joachim Eicher, Bernhard Freund, William B Hart, Christoph Lessmoellmann: Atomising nozzle and filter and spray generation device. Boehringer Ingelheim International, DMW, Sterne Kessler Goldstein & Fox, December 5, 1995: US05472143 (150 worldwide citation)

A nozzle assembly for use in atomizing and generating sprays from a fluid. The nozzle assembly includes two members joined together. In one of the two members are formed one or more nozzle outlets, one or more fluid inlets, and a plurality of channels that form filter passageways. The nozzle outlets ...