1
Yoram Palti: System for monitoring and controlling blood and tissue constituent levels. CB Carmel Biotechnology, Bryan Cave, November 29, 1994: US05368028 (393 worldwide citation)

Systems are disclosed which utilize implanted chemo-sensitive living cells to monitor tissue or blood concentration levels of chemicals. The implanted cells produce a detectable electrical, optical or chemical signal in response to changes in concentration in surrounding medium. The signal is then d ...


2
Yoram Palti: Implantable sensor chip. CB Carmel Biotechnology, Bryan Cave, David M Klein, May 7, 1996: US05513636 (371 worldwide citation)

An implantable sensor chip, which is preferably small enough to be injected through a hypodermic needle, includes a base constructed of an electrically insulating material, and at least one sensor for generating an output signal in the presence of a constituent or the existence of a condition. The s ...


3
Eduardo R Luque: Spinal fixation system. Biotechnology, Walker & McKenzie, April 3, 1990: US04913134 (357 worldwide citation)

A spinal fixation system for fixing vertebrae. A rigid elongated plate having openings is provided for being placed over the vertebrae. A plurality of screws having apertures extending along the longitudinal axis are provided for extending through the openings in the plate and into the vertebrae to ...


4
Yoram Palti: Implantable drug delivery pump. CB Carmel Biotechnology, Bryan Cave, David M Klein, December 12, 1995: US05474552 (348 worldwide citation)

A method and apparatus for maintaining the concentration of glucose in a person, animal or tissue within a predetermined range is disclosed. An implanted sensor of living cells produces a detectable electrical signal which varies with the concentration of glucose. A controller detects the electrical ...


5
Edmund G Tischer, Judith A Abraham, John C Fiddes, Richard L Mitchell: Production of vascular endothelial cell growth factor. California Biotechnology, Peter R Shearer, March 16, 1993: US05194596 (300 worldwide citation)

There is described an isolated vascular endothelial cell growth factor selected from the group consisting of bovine vascular endothelial cell growth factor of 120 amino acids and human vascular endothelial cell growth factor of 121 amino acids. The vascular endothelial cell growth factor is useful i ...


6
Eduardo R Luque: Spinal fixation method and system. Biotechnology, Walker & McKenzie, December 13, 1988: US04790297 (299 worldwide citation)

A method of and system for fixing one or more levels of the vertebrae of a spinal column. Elongated guide wires are provided for being inserted into the vertebrae. A rigid plate is provided for being placed over the vertebrae with the guide wires passing therethrough. Cannulated screws are provided ...


7
Philippe M Frossard: Apo AI/CIII genomic polymorphisms predictive of atherosclerosis. Biotechnology Research Partners, Ciotti & Murashige Irell & Manella, January 31, 1989: US04801531 (280 worldwide citation)

The invention offers an early detection method for atherosclerosis using genetic analysis to detect a polymorphisms shown to be correlated with this disease which are proximal to the apolipoprotein AI (apoAI) and aplipoprotein CIII (apoCIII) gene complex. All individuals with a 300 bp deletion 4 kb ...


8
Edward J Cook, Arthur P Lagace: Apparatus for forming emulsions. Biotechnology Development Corporation, George W Dishong, Richard J Hammond, August 6, 1985: US04533254 (264 worldwide citation)

Method and apparatus for forming emulsions, a term used to include microemulsions. The leading edges of a plurality of sheets of an emulsion-forming liquid mixture are forced under pressure to impinge in a low-pressure turbulent zone of the liquid. The apparatus comprises a plurality of nozzles havi ...


9
Oscar Jimenez, Frank J Bianco: Apparatus for testing physical condition of a subject. Biotechnology, Lowe King Price & Becker, January 11, 1983: US04367752 (252 worldwide citation)

The physical condition of a subject is tested by a transducer mounted on the subject which derives a first signal indicative of heart activity. An electronic instrument housing carried by the subject includes terminals responsive to the first signal and (a) an inertial member for monitoring the quan ...


10
Pablo Umaña, Joël Jean Mairet, James E Bailey: Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity. Glycart Biotechnology, Sterne Kessler Goldstein & Fox p l l c, August 5, 2003: US06602684 (224 worldwide citation)

The present invention relates to the field glycosylation engineering of proteins. More particular, the present invention is directed to the glycosylation engineering of proteins to provide proteins with improved therapeutic properties, e.g., antibodies, antibody fragments, or a fusion protein that i ...