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Luigi Catanzariti, Bryan W Kluttz, Geoff A McKinley, Arthur L Garland, Louis Graziano, James G Moe, Marcela Vera Garcia, James Clement Bishop, David Chastain, Fabio Gennari: Dual chamber disposable reaction vessel for amplification reactions, reaction processing station therefor, and methods of use. bioMerieux Vitek, McDonnell Boehnen Hulbert & Berghoff, July 28, 1998: US05786182 (116 worldwide citation)

A reaction vessel for a nucleic acid amplification reaction has a first chamber containing an amplification reagent mix, a second chamber containing an amplification enzyme, and a fluid channel or chamber connecting the first and second chambers together. A fluid sample is introduced into the first ...


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William Ernest Seaton, David B Shine, Craig Drager: Sample card transport method for biological sample testing machine. bioMerieux Vitek, McDonnell Boehnen Hulbert & Berghoff, September 23, 1997: US05670375 (95 worldwide citation)

A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card transport station has a drive belt and an associated stepper motor. The belt supports the card from one si ...


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Mark Joseph Fanning, Jean Pierre Bernard Gayral, Clifford W Karl, Bernard Jean Marie Limon, Donald Meyer, Roger James Morris, Ron Robinson, William Ernest Seaton, David B Shine, Paul Springer, Daniel Ray Williams, James Clement Bishop, Craig Drager, Thomas Burchard, David Chastain, Stephen Guerrera, Andrew Moore, David Porat, Arthur Rousmaniere, Andrew Zeigler: Automatic sample testing machine. bioMerieux Vitek, McDonnell Boehnen Hulbert & Berghoff, June 9, 1998: US05762873 (90 worldwide citation)

An automatic sample testing machine for testing samples stored in test cards. The machine has a test sample positioning system for moving a tray containing a plurality of test sample cards and fluid receptacles among various stations in the machine. The machine has a diluting station for adding a pr ...


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Hermanus Johannes Maria Kreuwel, Emiel Gerebern Maria Verwimp: Device and method for mixing magnetic particles with a fluid. bioMerieux, Myers Bigel Sibley & Sajovec PA, July 20, 2004: US06764859 (87 worldwide citation)

This invention relates to the use of magnetic or magnetizable particles, and, in particular, to methods of mixing magnetic or (super)paramagnetic particles efficiently with a fluid and the separation of the magnetic particles from a fluid, optionally followed by resuspension of the particles in anot ...


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J Lawrence Burg, Luigi Catanzariti, Bryan W Kluttz, Geoff A McKinley, James G Moe, Marcela Vera Garcia: Nucleic acid assays. bioMerieux Vitek, Lisa M W Hillman, McDonnell Boehnen Hulbert & Berghoff, October 9, 2001: US06300068 (81 worldwide citation)

The present invention relates to the detection of specific nucleic acid sequences after an amplification process, or directly without amplification. In particular, the invention provides for the automation of the amplification and detection process, the amplification and detection of one or more spe ...


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J Lawrence Burg, Luigi Catanzariti, Marcela Vera Garcia, James G Moe: Device for automated detection of nucleic acids. bioMerieux Vitek, McDonnell Boehnen Hulbert & Berghoff, July 1, 2003: US06586234 (70 worldwide citation)

The present invention relates to the detection of specific nucleic acid sequences after an amplification process, or directly without amplification. In particular, the invention provides for the automation of the amplification and detection process, the amplification and detection of one or more spe ...


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Gregory R Maes, Dennis M Connor, Brent D Freiner, Clifford W Karl, Ron Robinson, Raymond M Shelton, Garry R Tegeler, Michael James Justin: Incubation station for test sample cards. bioMerieux, McDonnell Boehnen Hulbert & Berghoff, December 5, 2000: US06156565 (63 worldwide citation)

An incubation station has a carousel for receiving a plurality of test sample cards. An even temperature and air flow distribution inside the carousel and incubation of the cards over time at the proper temperature was found to be critically dependent upon air flow characteristics within the incubat ...


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Luigi Catanzariti, Bryan W Kluttz, Bruno Colin, Cecile Jaravel: Dual chamber disposable reaction vessel for amplification reactions. bioMerieux, McDonnell Boehnen Hulbert & Berghoff, November 23, 1999: US05989499 (62 worldwide citation)

A reaction vessel for a nucleic acid amplification reaction has a first chamber containing an amplification reagent mix, a second chamber containing an amplification enzyme, and a fluid channel or chamber connecting the first and second chambers together. A fluid sample is introduced into the first ...


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Francis Garnier, Bernard Mandrand, Patrick Broyer, Pierre Imbaud: Valves activated by electrically active polymers or by shape-memory materials, device containing same and method for using same. Biomerieux, James C Lydon, February 7, 2006: US06994314 (47 worldwide citation)

This invention concerns a valve (2), with at least one channel (3) running through it, allowing a fluid (F3) to be directed by transfer means within a device (1), the device (1) featuring at least one face (4), possibly flat, the valve (2) consisting of a film (7 or 16), flexible and/or which can be ...


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