1
Stephanie L Castro, Emilio Barbera Guillem: Functionalized nanocrystals and their use in detection systems. BioCrystal, M Bud Nelson, September 5, 2000: US06114038 (222 worldwide citation)

Provided are compositions comprising water-soluble, functionalized nanocrystals. The water-soluble functionalized nanocrystals comprise quantum dots capped with a layer of a capping compound, and further comprise, by operably linking and in a successive manner, one or more additional compounds. The ...


2
Emilio Barbera Guillem: Fluorescent ink compositions comprising functionalized fluorescent nanocrystals. Biocrystal, Raymond A Miller, Pepper Hamilton, June 10, 2003: US06576155 (121 worldwide citation)

A fluorescent ink composition comprising functionalized fluorescent nanocrystals, an aqueous-based ink carrier comprising water or a water-based solution, and a binder. Also provided are methods of providing an image or a security mark on a substrate for subsequent identification by applying a fluor ...


3
Emilio Barbera Guillem, Marlin O Thurston: Continuous flow process for production of semiconductor nanocrystals. BioCrystal, M Bud Nelson, January 30, 2001: US06179912 (89 worldwide citation)

Provided is a system and continuous flow process for producing monodisperse semiconductor nanocrystals comprising reservoirs for the starting materials, a mixing path in which the starting materials are mixed, a first reactor in which the mixture of starting materials is mixed with a coordinating so ...


4
Emilio Barbera Guillem: Automated cell management system for growth and manipulation of cultured cells. Biocrystal, Benesch Friedlander Coplan & Aronoff, January 6, 2004: US06673595 (72 worldwide citation)

An automated cell management system which can be programmed to perform and control various operations of the essential phases of cell culturing, of cell culture manipulation, and of cell culture evaluation. The automated cell management system comprises a housing, a storage array for accommodating a ...


5
Emilio Barbera Guillem: Cell culture apparatus and method for culturing cells. BioCrystal, Raymond A Miller, Benesch Friedlander Coplan & Aronoff, September 24, 2002: US06455310 (71 worldwide citation)

Provided is a cell culture apparatus for culturing cells, and optionally, for performing magnetic separation of cells desired to be cultured. The cell culture apparatus preferably comprises a frame; two membranes, preferably each being gas permeable, which are securedly sealed in a leak-proof selain ...


6
Emilio Barbera Guillem, M Bud Nelson: Cell culture apparatus and methods of use. BioCrystal, Benesch Friedlander Coplan & Aronoff, June 25, 2002: US06410309 (55 worldwide citation)

Provided is a cell culture apparatus for culturing cells, and optionally, for performing magnetic separation of cells desired to be cultured. The cell culture apparatus preferably comprises a frame; at least one gas permeable membrane securedly sealed in a leak-proof sealing to a frame and an opposi ...


7
Emilio Barbera Guillem: Device having microchambers and microfluidics. BioCrystal, Benesch Friedlander Coplan & Aronoff, November 2, 2004: US06811752 (55 worldwide citation)

Provided is a device comprising a plurality of microchambers having a closed vented environment, wherein each microchamber is in operative communication with a filling port and a vent aperture. The device further comprises a base which is sandwiched between two liquid-impermeable membranes, with at ...


8
Emilio Barbera Guillem, Rick D Lucas: Microincubator comprising a cell culture apparatus and a transparent heater. BioCrystal, M Bud Nelson, April 29, 2003: US06555365 (46 worldwide citation)

Provided for heating cultured cells is a controlled heater device comprising a cell culture apparatus, a transparent heater in thermal contact with the cell culture apparatus, and may further comprise one or more of a transparent filter provided to prevent a predetermined spectral range of light fro ...


9
Emilio Barbera Guillem: Immunotherapy of B cell involvement in progression of solid, nonlymphoid tumors. BioCrystal, M Bud Nelson, May 1, 2001: US06224866 (40 worldwide citation)

A method for treating a pro-tumor immune response in an individual having, or suspected of having, a pro-tumor immune response, by administering a therapeutically effective amount of an immunotherapeutic composition which binds to a determinant on B cells, resulting in B cell depletion including of ...


10
Emilio Barbera Guillem, Stephanie L Castro: Fluorescent nanocrystal-embedded microspheres for fluorescence analysis. Biocrystal, Raymond A Miller, Pepper Hamilton, January 20, 2004: US06680211 (38 worldwide citation)

Provided are a fluorescent microsphere comprised of a plurality of fluorescent nanocrystals embedded in a polymeric microsphere; a kit prepared from the fluorescent microspheres; and a method of producing the fluorescent microspheres comprising swelling the polymeric microsphere so that into its por ...