1
Mark A Hollis, Daniel J Ehrlich, R Allen Murphy, Bernard B Kosicki, Dennis D Rathman, Chang Lee Chen, Richard H Mathews, Barry E Burke, Mitch D Eggers, Michael E Hogan, Rajender Singh Varma: Optical and electrical methods and apparatus for molecule detection. Massachusetts Institute of Technology, Houston Advanced Research Center, Baylor College of Medicine, Hamilton Brook Smith & Reynolds P C, August 5, 1997: US05653939 (399 worldwide citation)

A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular str ...


2
Michael E Hogan, Donald J Kessler: Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use. Baylor College of Medicine, Fulbright & Jaworski, January 5, 1993: US05176996 (196 worldwide citation)

A method for making synthetic oligonucleotides which bind to target sequences in a duplex DNA forming colinear triplexes by binding to the major groove. The method includes scanning genomic duplex DNA and identifying nucleotide target sequences of greater than about 20 nucleotides having either abou ...


3
Nils A Normann: Method and apparatus for recording activity in intact nerves. Baylor College of Medicine, Fulbright & Jaworski, May 18, 1976: US03957036 (188 worldwide citation)

A method and apparatus is provided which will attenuate bioelectric interference when measuring the activity in an intact nerve. An electrode probe is provided having first and second electrodes positioned on opposite sides of a thin, flexible, insulating carrier. The probe is inserted between the n ...


4
John M Corman: Retractable scalpel with blade-activated lock. Baylor College of Medicine, Bush Moseley & Riddle, November 2, 1993: US05258001 (183 worldwide citation)

In accordance with illustrative embodiments of the present invention as disclosed herein, a retractable blade knife particularly adapted for use as a surgical scalpel or the like includes a thin metal blade positioned in a cavity inside a handle and being movable between an extended position and a r ...


5
Britton Chance, Claudia S Robertson: Lateralization spectrophotometer. Non Invasive Technology, Baylor College of Medicine, Fish & Richardson P C, February 23, 1999: US05873821 (154 worldwide citation)

The present invention utilizes differential measurement of radiation that migrated into two migration paths between two source-detector pairs placed on the head in a manner that each path is localized in a portion of one hemisphere of the brain. The present invention also provides various embodiment ...


6
Rabih O Darouiche, Issam Raad: Antimicrobial impregnated catheters and other medical implants. Baylor College of Medicine Board of Regents, The University of Texas System, Thomas D Paul, Fulbright & Jaworski L, May 11, 1999: US05902283 (148 worldwide citation)

A non-metallic antimicrobial impregnated medical implant, such as a catheter, and a method for impregnating a non-metallic medical implant with an antimicrobial agent is provided. The method for making the impregnated implant comprises the steps of forming an antimicrobial composition of an effectiv ...


7
T William Hutchens, Tai Tung Yip: Method and apparatus for desorption and ionization of analytes. Baylor College of Medicine, Fulbright & Jaworski L, February 17, 1998: US05719060 (139 worldwide citation)

This invention relates generally to methods and apparatus for desorption and ionization of analytes for the purpose of subsequent scientific analysis by such methods, for example, as mass spectrometry or biosensors. More specifically, this invention relates to the field of mass spectrometry, especia ...


8
T William Hutchens, Tai Tung Yip: Surface-enhanced photolabile attachment and release for desorption and detection of analytes. Baylor College of Medicine, Fulbright & Jaworski L, September 26, 2000: US06124137 (131 worldwide citation)

This invention is directed to systems for presenting an analyte to an energy source for desorption in methods of analytic detection, such as mass spectrometry. The probes have a layer of energy absorbing molecules on their surface which absorbs energy form the energy source, thereby enabling desorpt ...


9
Charles T Caskey, Albert O Edwards: DNA typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats. Baylor College of Medicine, Fulbright & Jaworski, November 15, 1994: US05364759 (126 worldwide citation)

The present invention relates to a DNA profiling assay for detecting polymorphisms in a short tandem repeat. The method includes the steps of extracting DNA from a sample to be tested, amplifying the extracted DNA and identifying the amplified extension products for each different sequence. Each dif ...


10
Isaam Raad, Robert Sherertz: Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices. Board of Regents The University of Texas System, Baylor College of Medicine, Wake Forest University, Arnold White & Durkee, November 18, 1997: US05688516 (123 worldwide citation)

Compositions and methods of employing compositions in flushing and coating medical devices are disclosed. The compositions include selected combinations of a chelating agent, anticoagulant, or antithrombotic agent, with an non-glycopeptide antimicrobial agent, such as the tetracycline antibiotics. M ...