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Hans Helmut Goertz, Stefan Marcinowski, Axel Sanner: Water-insoluble protein material, its preparation and its use. BASF Aktiengesellschaft, Keil & Weinkauf, October 23, 1984: US04478976 (287 worldwide citation)

A biologically active protein which is bonded to a water-insoluble porous copolymer based on N-vinylimidazole and/or substituted N-vinylimidazoles and monomers which can be copolymerized therewith, its preparation and its use for carrying out enzymatic reactions.


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Jochen G Salfeld, Deborah J Allen, Hendricus R J M Hoogenboom, Zehra Kaymakcalan, Boris Labkovsky, John A Mankovich, Brian T McGuinness, Andrew J Roberts, Paul Sakorafas, David Schoenhaut, Tristan J Vaughan, Michael White, Alison J Wilton: Human antibodies that bind human TNF.alpha.. BASF Aktiengesellschaft, Catherine J Kara, Elizabeth A Hanley Esq, Lahive & Cockfield, July 18, 2000: US06090382 (269 worldwide citation)

Human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor .alpha. (hTNF.alpha.) are disclosed. These antibodies have high affinity for hTNF.alpha. (e.g., K.sub.d =10.sup.-8 M or less), a slow off rate for hTNF.alpha. dissociation (e.g., K.sub.of ...


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Eberhard Steckhan, Rainer Wienkamp: Electrochemical hydrogenation of nicotinamide adenine dinucleotide. BASF Aktiengesellschaft, Keil & Weinkauf, July 2, 1985: US04526661 (240 worldwide citation)

Nicotinamide adenine dinucleotide (NAD.sup..sym.) is electrochemically hydrogenated to NADH in aqueous solution and in the presence of a metal complex as an electron carrier.


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Achim Moeller, Franz Emling: Monoclonal antibodies against human tumor necrosis factor (TNF), and use thereof. BASF Aktiengesellschaft, Oblon Spivak McClelland Maier & Neustadt, July 27, 1993: US05231024 (206 worldwide citation)

New hybridoma cell lines which synthesize highly specific monoclonal antibodies (mAb) against human tumor necrosis factor (TNF), monoclonal antibodies against TNF, a process for the preparation of such hybridoma cell lines and antibodies, and the use of the monoclonal antibodies are described.


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Paul Boerzel, Klaus Bronstert, Friedrich Hovemann: Polyisobutenes. BASF Aktiengesellschaft, Keil & Witherspoon, May 1, 1979: US04152499 (203 worldwide citation)

Isobutene polymers having a mean degree of polymerization P of from 10 to 100 and a proportion E of double bonds, capable of reaction with maleic anhydride, of from 60 to 90%, where E=100% corresponds to the calculated theoretical value for the case where each molecule of the isobutene polymer conta ...


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Schuster Ludwig, Franz Josef Mueller, Axel Anderlohr, Peter Blei, Gerhart Eigenberger, Bernd Hoppner, Gerd Kaibel, Wolfgang Steiner: Continuous preparation of ethanol. BASF Aktiengesellschaft, John H Shurtleff, May 14, 1985: US04517391 (176 worldwide citation)

Ethanol is prepared by hydrogenating acetic acid under superatmospheric pressure and at elevated temperatures by a process wherein a predominantly cobalt-containing catalyst is used and acetic acid and hydrogen are passed through the reactor, at from 210.degree. to 330.degree. C. and under from 10 t ...


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