1

2
Ishikawa Kiyofumi, Fukami Takehiro, Hayama Takashi, Niiyama Kenji, Nagase Toshio, Mase Toshiaki, Fujita Kagari, Ihara Masaki, Ikemoto Fumihiko, Yano Mitsuo: Endothelin antagonistic peptide derivatives.. Banyu Pharma, December 11, 1991: EP0460679-A2 (83 worldwide citation)

1. A peptide derivative of the formula: wherein A is a group of the formula R-CO- {wherein R is a lower alkyl group, a cycloalkyl group, a cycloalkyl lower alkyl group, a group of the formula Ar-(CH2)p-(wherein Ar is a phenyl group, a furyl group or a thienyl group, and p is 0, 1 or 2), a 1,3-dithio ...


3
Kiyofumi Ishikawa C O Banyu Ph, Takehiro Fukami C O Banyu Phar, Takashi Hayama C O Banyu Pharm, Kenji Niiyama C O Banyu Pharm, Toshio Nagase C O Banyu Pharm, Toshiaki Mase C O Banyu Pharm, Kagari Fujita C O Banyu Pharm, Masaru Nishikibe C O Banyu Pha, Masaki Ihara C O Banyu Pharm C, Mitsuo Yano C O Banyu Pharm Co: Endothelin atagonistic cyclic pentapeptides.. Banyu Pharma, July 10, 1991: EP0436189-A1 (72 worldwide citation)

1. A cyclic pentapeptide of the formula: wherein X (n = 1-5) represent amino acid residues, respectively, and X is DPhe, DTyr, DTha, DTza, DNal, DBta, DTrp, DTrp(O), DTrp(CHO) or DTrp((CH2)mCOR) (wherein m is from 0 to 6, and R is a hydroxyl group, a C1-C6 alkoxy group, an amino group or a C1-C6 mon ...


4
Mase Toshiaki, Mitsuya Morihiro, Kobayashi Kensuke, Noguchi Kazuhito: Substituted heteroaromatic derivatives. Banyu Pharma, September 9, 1998: EP0863141-A1 (44 worldwide citation)

This invention provides substituted heteroaromatic ring derivatives which are represented by a general formula ÄIÜ below: Äin the formula, R and R may be same or different and each signifies hydrogen, halogen or lower alkyl; R signifies C3-C6 cycloalkyl or cycloalkenyl; R signifies a heteroaromatic ...


5
Tsuchiya Yoshimi, Nomoto Takashi, Ohsawa Hirokazu, Kawakami Kumiko, Ohwaki Kenji, Nishikibe Masaru: Fluorinated 1,4-disubstituted piperidine derivatives. Banyu Pharma, July 21, 1999: EP0930298-A1 (41 worldwide citation)

This invention relates to novel fluorine-containing 1,4-disubstituted piperidine derivatives represented by a general formula ÄIÜ and pharmaceutically acceptable salts thereof, Äwherein: Ar represents an aryl group or a hetero-aryl group having 1 to 2 hetero atoms selected from a group consisting of ...


6
Iino Tomoharu, Hashimoto Noriaki, Nakashima Hiroshi, Takahashi Keiji, Nishimura Teruyuki, Eiki Jun Ichi: Heteroarylcarbamoylbenzene derivative. Banyu Pharma, November 30, 2005: EP1600442-A1 (38 worldwide citation)

Compounds having glucokinase activating effects and being useful as treatments for diabetes, which are represented by the following formula (I): Äwherein X represents oxygen, etc., X represents oxygen, etc., R represents a group on Ring A such as alkylsulfonyl, etc., R represents C3-7 cyclic alkyl o ...


7
Hayama Takashi, Hayashi Kyoko, Honma Teruki, Takahashi Ikuko: Biarylurea derivatives. Banyu Pharma, April 24, 2002: EP1199306-A1 (36 worldwide citation)

The present invention relates to a compound of Formula (I) and the manufacturing method(s) thereof and the use thereof: ,wherein: Ar is a nitrogen-containing heteroaromatic ring group; X and Z are each a carbon atom, and so on; Y is CO, and so on; R1 is a hydrogen atom, and so on; R2 and R3 are each ...


8
Morishima Hajime, Koike Yutaka, Nakano Masato, Atsuumi Shugo, Tanaka Seiichi, Matsuyama Kenji: N-acylamino acid derivatives and their use.. Banyu Pharma, April 5, 1989: EP0309766-A2 (30 worldwide citation)

An N-acylamino acid derivative of the formula: wherein each of R, R, R and R is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms; each of R and R is hydrogen or lower alkyl; A is -CH(OH)-(CH2)qR where ...


9
Nonoshita, Ogino, Ishikawa, Sakai, Nakashima, Nagae, Tsukahara, Arakawa, Nishimura, Eiki: Novel 2-heteroaryl-substituted benzimidazole derivative. Banyu Pharma, September 20, 2006: EP1702919-A1 (28 worldwide citation)

A glucokinase activator is provided; and a remedy and/or a preventive for diabetes, or a remedy and/or a preventive for diabetes such as retinopathy, nephropathy, neurosis, ischemic cardiopathy, arteriosclerosis, and further a remedy and/or a preventive for obesity are provided. A glucokinase activa ...


10
Hiroharu Arakawa, Hiroyuki Suda, Hisao Kondo, Katsuhisa Kojiri, Ohkubo Mitsuru: Indolopyrrolocarbazole derivatives.. Banyu Pharma, June 9, 1993: EP0545195-A1 (26 worldwide citation)

A compound represented by the following general formula and a pharmaceutically acceptable salt thereof wherein R and R each independently represent a hydrogen atom, lower alkyl group, lower alkenyl group, lower alkynyl group, aryl group, aralkyl group or heterocyclic group (the alkyl group, lower al ...



Click the thumbnails below to visualize the patent trend.