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LEE Kwangho, NIU Deqiang, PETTER Russell C, BAEVSKY Matthew Frank, SINGH Juswinder: COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS, HETEROCYCLIC COMPOUNDS AND USES THEREOF. AVILA THERAPEUTICS, LEE Kwangho, NIU Deqiang, PETTER Russell C, BAEVSKY Matthew Frank, SINGH Juswinder, BUTEAU Kristen C, May 10, 2012: WO/2012/061299 (32 worldwide citation)

Heterocyclic pyrimidine compounds that modulate mutant-selective epidermal growth factor receptor (EGFR) kinase activity are disclosed. Selectivity in inhibition of various mutant-EGFR is disclosed. Pharmaceutical compositions containing the pyrimidine derivatives, and methods of treating diseases a ...