1
Richard L Dunn, Arthur J Tipton, George L Southard, Jack A Rogers: Biodegradable polymer composition. Atrix Laboratories, Merchant Gould Smith Edell Welter & Schmidt, June 28, 1994: US05324519 (280 worldwide citation)

The invention is directed to a composition composed of a thermoplastic or thermosetting polymer which is capable of forming a biodegradable and/or bioerodible microporous, solid or gelatinous polymer matrix. The matrix is useful as an implant in animals for enhancing regeneration of cells and tissue ...


2
Richard L Dunn, James P English, Donald R Cowsar, David P Vanderbilt: Biodegradable in-situ forming implants and methods of producing the same. Atrix Laboratories, Merchant Gould Smith Edell Welter & Schmidt, January 11, 1994: US05278201 (255 worldwide citation)

A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a ...


3
Richard L Dunn, James P English, Donald R Cowsar, David D Vanderbilt: Biodegradable in-situ forming implants and methods of producing the same. Atrix Laboratories, Merchant Gould Smith Smith Edell & Welter, January 11, 1994: US05278202 (218 worldwide citation)

A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a ...


4
Richard L Dunn: Non-polymeric sustained release delivery system. Atrix Laboratories, Merchant Gould Smith Edell Welter & Schmidt, March 30, 1999: US05888533 (203 worldwide citation)

The invention relates to a method and composition for forming an implant in-situ within a body using non-polymeric materials, and the use of such implants as medical devices and drug delivery systems. The composition can be applied to an animal to treat periodontal disease or other tissue defect, en ...


5
Richard L Dunn, Arthur J Tipton: Polymeric compositions useful as controlled release implants. Atrix Laboratories, Merchant Gould Smith Edell Welter & Schmidt, December 30, 1997: US05702716 (192 worldwide citation)

The invention is directed to an improved system for controlled release of biologically active materials and to a liquid composition for its formation. The liquid composition is composed of a thermoplastic polymer, rate modifying agent, bioactive material and organic solvent. The liquid composition i ...


6
Richard L Dunn: Non-polymeric sustained release delivery system. Atrix Laboratories, Merchant Gould Smith Edell Welter and Schmidt, April 7, 1998: US05736152 (179 worldwide citation)

The invention relates to a method and composition for forming an implant in-situ within a body using non-polymeric materials, and the use of such implants as medical devices and drug delivery systems. The composition can be applied to an animal to treat periodontal disease or other tissue defect, en ...


7
Alan M Polson, Deryl D Swanbom, Richard L Dunn, Charles P Cox, Richard L Norton, Bryan K Lowe, Kenneth S Peterson: Biodegradable implant precursor. Atrix Laboratories, Merchant Gould Smith Edell Welter & Schmidt, January 30, 1996: US05487897 (170 worldwide citation)

The invention is directed to a biodegradable implant precursor having a two-part structure made of an outer sac and a liquid content. The implant precursor is composed of a biodegradable, water-coagulable thermoplastic polymer and a water-miscible organic solvent. When administered to an implant sit ...


8
Richard L Dunn, James P English: Biodegradable polymer composition. Atrix Laboratories, Schwegman Lundberg Woessner & Kluth P A, October 8, 2002: US06461631 (169 worldwide citation)

A flowable composition containing a biocompatible, biodegradable, branched thermoplastic polymer is used to form solid matrices such as implants and controlled-release, drug-compositions in a body. The flowable composition with or without bioactive agent can be administered by syringe and needle to ...


9
Richard L Norton, Stephen Michael Gregory Knight, Arthur J Tipton: Biodegradable polymeric composition. Atrix Laboratories, Merchant & Gould Smith Edell Welter & Schmidt, October 28, 1997: US05681873 (161 worldwide citation)

The invention provides moldable, biodegradable composition for use with bone and other tissues. The composition comprises a poly(caprolactone) thermoplastic polymer processed alone or compounded with a biocompatible, biodegradable substance that controls crystallization of the polymer and functions ...


10
Gerald L Yewey, Nancy L Krinick, Richard L Dunn, Michael L Radomsky, Gerbrand Brouwer, Arthur J Tipton: Liquid delivery compositions. Atrix Laboratories, Merchant Gould Smith Edell Welter & Schmidt, July 14, 1998: US05780044 (140 worldwide citation)

Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The ...