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George R Pettit, Sheo B Singh: Synthesis of dolastatin 10. Arizona Board of Regents, Richard R Mybeck, December 18, 1990: US04978744 (48 worldwide citation)

A complicated but extremely important scheme of synthesis has been developed for synthesizing, dolaisoleuine, dolaproine, dolaphenine and dolavaline from readily available starting materials such as Z-(S,S)isoleucine, S-phenylalaline, S-phenylalaninol, S-prolinol, S-mandelate, and S-valine. The requ ...


52
George R Pettit, Jayaram K Srirangam, Michael D Williams: Human cancer inhibitory peptide amides. Arizona Board of Regents acting on behalf of Arizona State University, Richard R Mybeck, Walter R Mybect II, June 25, 1996: US05530097 (45 worldwide citation)

This application discloses seven newly synthesized pentapeptide amides and our tetrapeptide amides. The synthesis utilized both naturally occurring and modified amino acids; the modified amino acids are constituents of the well known dolastatin 10 and dolastatin 15 which are structurally distinct pe ...


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George R Pettit, Jozsef Barkoczy, Darko Kantoci: Human cancer inhibitory pentapeptide amides. Arizona Board of Regents acting on behalf of Arizona State University, Richard R Mybeck, April 25, 1995: US05410024 (43 worldwide citation)

The synthesis of useful peptides presents a promising approach to new theeutic agents. The Dolastatins, a series of linear and cyclic antineoplastic and/or cytostatic peptides isolated from Indian Ocean sea hare Dolabella auricularia represent excellent leads for synthetic modification.


54
Harrison H Barrett, Daniel G Marks, H Bradford Barber, Joshua D Eskin: Signal processing method for gamma-ray semiconductor sensor. The Arizona Board of Regents on Behalf of the University of Arizona, Antonio R Durando, October 20, 1998: US05825033 (43 worldwide citation)

A CdZnTe detector array with pixel electrodes indium-bump-bonded to a multiplexer readout circuit. The pixel size is selected so as to minimize the effect of hole trapping while ensuring that all interacting electrons deposit their energy in a designated central pixel. The readout is carried out eit ...


55
Victor J Huby, Sejin Lim, Wei Yuan: Melanocortin receptor antagonists and agonists. The Arizona Board of Regents on Behalf of the University of Arizona, Yahwak & Associates, April 25, 2000: US06054556 (43 worldwide citation)

Cyclic lactam peptides are disclosed which inhibit at various levels of antagonism the melanocortin 1 receptor (MC1R), melanocortin 3 receptor (MC3R), melanocortin 4 receptor (MC4R), and Melanocortin 4 receptor (MC5R).


56
Hu Qiang, Summerfeld Milton: Novel chlorella species and uses therefor. Arizona Board Of Regents A Body Corporate Of The State Of Az Acting For & On Behalf Of Az State Unviversity, Hu Qiang, Summerfeld Milton, OSLICK Sherri L, November 22, 2007: WO/2007/134294 (43 worldwide citation)

The present invention relates to algal species and compositions, methods for identifying algae that produce high lipid content, possess tolerance to high CO2, and/or can grow in wastewater,, and methods for using such algae for lipid production, wastewater remediation, waste gas remediation, and/or ...


57
Timothy L Porter, Michael P Eastman: Microcantilever sensor. Arizona Board of Regents, Christie Parker & Hale, February 25, 2003: US06523392 (42 worldwide citation)

An apparatus and method for sensing chemical and/or biological analytes includes a deflectable arm of a microcantilever formed over and contacting a sensing element. A gaseous or liquid medium which may include the analyte being detected, is introduced to the sensing element. The sensing element und ...


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Raymond K Kostuck: Reconfigurable substrate-mode holographic interconnect apparatus and method. Arizona Board of Regents For and On Behalf of the University of Arizona, Victor Flores, August 7, 1990: US04946253 (40 worldwide citation)

The present invention discloses a reconfigurable optical interconnect apptus that redirects an optical beam through embedded holographic elements of a substrate-mode hologram to connecting information processors or to photonic switching devices. The apparatus includes a substrate-mode hologram, incl ...


60
Stuart M Lindsay: Cell and substrate for electrochemical STM studies. Arizona Board of Regents Arizona State University, Richard R Mybeck, September 19, 1989: US04868396 (40 worldwide citation)

A cell and substrate for use with a scanning tunneling microscope to image molecules adsorbed on a noble metal surface disposed under solvent in conducting electrochemical studies and methods for preparing atomically flat metal surfaces as the substrates for the STM and for plating molecules onto th ...



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