1
Keiji Iwasaki, Yuji Iwashita, Taketoshi Okami: Hemoglobin combined with a poly(alkylene oxide). Ajinomoto Co, Oblon Fisher Spivak McClelland & Maier, June 2, 1987: US04670417 (544 worldwide citation)

There is disclosed hemoglobin modified in that a poly(alkylene oxide) is bonded thereto by a bond between a terminal group of said poly(alkylene oxide) and an amino group of said hemoglobin, said bond having the structure:


2
Yuji Iwashita, Katsumi Ajisaka: Blood substitute containing modified hemoglobin. Ajinomoto Company Incorporated, Oblon Fisher Spivak McClelland & Maier, November 17, 1981: US04301144 (419 worldwide citation)

A novel modified hemoglobin was prepared. The hemoglobin is coupled with a polyalkylene glycol or its derivative, and the products are useful as a blood substitute. The oxygen-carrying capacity of this hemoglobin is nearly equal to that of a native hemoglobin, and the residence time in the circulati ...


3
Katsumi Niki, Katsuyoshi Kobayashi, Hiroo Inoguchi, Tatsuhiko Yagi: Chemically modified electrodes and their uses. Ajinomoto Company Incorporated, Oblon Fisher Spivak McClelland & Maier, October 28, 1986: US04619754 (387 worldwide citation)

An electrically conducting solid electrode having a surface on which a nitrogen-containing electron mediator and a strong acidic cation exchange resin containing aromatic groups are immobilized is disclosed along with methods for producing this electrode and uses therefor.


4
Yasuhiro Kimura, Katsumi Niki: Modified electrode. Ajinomoto Co, Oblon Fisher Spivak McClelland & Maier, June 17, 1986: US04595479 (321 worldwide citation)

A chemically modified electrode comprising a pyrolytic graphite surface, wherein the basal plane of graphite is exposed on said surface and a redox/adsorption electron mediator is irreversibly absorped directly onto the basal plane of graphite on said surface, is disclosed along with methods of usin ...


5
Eiko Ohtsuka, Hideo Inoue, Hirokazu Morisawa, Susumu Shibahara, Sachiko Mukai, Tohru Nishihara: Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers. Ajinomoto Co, Oblon Spivak McClelland Maier & Neustadt, May 7, 1991: US05013830 (235 worldwide citation)

There is disclosed a compound having a double chain which is composed of an RNA (+chain) and a complementary DNA (-chain), wherein a portion of the DNA (-chain) has been replaced by an RNA or a derivative thereof, and wherein, when the compound is subjected to the action of an enzyme having a ribonu ...


6
Yuji Iwashita, Katsumi Ajisaka, Keiji Iwasaki: Oxygen carrier. Ajinomoto Company Incorporated, Oblon Fisher Spivak McClelland & Maier, November 1, 1983: US04412989 (214 worldwide citation)

An oxygen carrying material containing hemoglobin or a hemoglobin derivative covalently coupled through an amide bond to a polymer selected from the group consisting of polyethylene glycol, polypropylene glycol, and copolymers of ethylene oxide and propylene oxide.


7
Yumioka Ryosuke, Ishii Hiroji, Koyama Masako: Cosmetic composition. Ajinomoto, July 14, 1999: EP0928608-A2 (98 worldwide citation)

An N-long-chain acyl neutral amino acid ester containing a straight-chain or branched-chain, saturated or unsaturated acyl group having from 6 to 22 carbon atoms, where the hydrocarbon group of the alcohol constituting the ester is a straight-chain or branched-chain, saturated or unsaturated hydroca ...


8
Tadaomi Saito, Yoshimasa Matsuzawa, Sadayoshi Ninagawa, Masao Honna, Masahiko Takesada, Masahiro Takehara: Gels of nonpolar liquids with N-acyl amino acids and derivatives thereof as gelling agents. Ajinomoto, Oblon Fisher Spivak McClelland & Maier, July 13, 1976: US03969087 (94 worldwide citation)

A wide variety of non-polar organic liquids are converted into gels by homogeneously admixing the non-polar organic liquids with a small amount of certain N-acyl amino acids or derivatives of N-acyl amino acids such as esters, amides and amine salts of the N-acyl amino acids.


9
Makoto Iwatsuki, Toshio Hayashi: Silk-fibroin and human-fibrinogen adhesive composition. Ajinomoto Co, Oblon Fisher Spivak McClelland & Maier, April 4, 1989: US04818291 (88 worldwide citation)

The present invention provides a novel adhesive which contains a mixture of human-fibrinogen and silk-fibroin and which is suitable especially for use in surgery. The mixing ratio of silk-fibroin to human-fibrinogen is 5 to 90, preferably 20 to 70% by weight.


10
Masao Motoki, Atsushi Okiyama, Masahiko Nonaka, Haruo Tanaka, Ryosuke Uchio, Akira Matsuura, Hiroyasu Ando, Koichi Umeda: Transgultaminase. Ajinomoto Co, Amano Pharmaceutical, Oblon Spivak McClelland Maier & Neustadt, October 20, 1992: US05156956 (84 worldwide citation)

A transglutaminase catalyzing an acyl transfer reaction of a .gamma.-carboxyamide group of a glutamine residue in a peptide or protein chain in the absence of Ca.sup.2+.