1
Vijai Kumar, David Dixon, Divya Tewari, Dilip B Wadgaonkar: Methods and compositions for deterring abuse of opioid containing dosage forms. Acura Pharmaceuticals, Morgan Lewis & Bockius, April 10, 2007: US07201920 (144 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


2
Kumar Vijai, Dixon David, Tewari Divya, Wadgaonkar Dilip B: Methods and compositions for deterring abuse of opioid containing dosage forms. Acura Pharmaceuticals, Kumar Vijai, Dixon David, Tewari Divya, Wadgaonkar Dilip B, HALLIDAY Christopher, June 16, 2005: WO/2005/053587 (62 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


3
Vijai Kumar, David Dixon, Divya Tewari, Dilip B Wadgaonkar: Extended release opioid abuse deterrent compositions and methods of making same. Acura Pharmaceuticals, Morgan Lewis & Bockius, January 24, 2012: US08101630 (53 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


4
Vijai Kumar, David Dixon, Divya Tewari, Dilip B Wadgaonkar: Methods and compositions for deterring abuse of opioid containing dosage forms. Acura Pharmaceuticals, Morgan Lewis & Bockius, March 31, 2009: US07510726 (47 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


5
Vijai Kumar, David Dixon, Divya Tewari, Dilip B Wadgaonkar: Extended release opioid abuse deterrent compositions and methods of making same. Acura Pharmaceuticals, Morgan Lewis & Bockius, April 2, 2013: US08409616 (34 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


6
Charles Auxilium Francis, Zhaiwei Lin, Christopher Arne Kaldahl, Kazimierz Grzegorz Antczak, Vijai Kumar: Process for manufacturing opioid analgesics. Acura Pharmaceuticals, Morgan Lewis & Bockius, July 4, 2006: US07071336 (33 worldwide citation)

Oxycodone is manufactured in high yields and with a high purity using a composition including a thebaine component into 14-hydroxycodeinone and then reduction of 14-hydroxycodeinone to oxycodone.


7
Vijai Kumar, David Dixon, Divya Tewari, Dilip B Wadgaonkar: Methods and compositions for deterring abuse of drugs susceptible to abuse and dosage forms thereof. Acura Pharmaceuticals, Morgan Lewis & Bockius, July 19, 2011: US07981439 (25 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


8
Emigh James F, Reddick Andrew D, Spivey Ron J, Leech Ronald L: Methods and compositions for deterring abuse of orally administered pharmaceutical products. Acura Pharmaceuticals, Emigh James F, Reddick Andrew D, Spivey Ron J, Leech Ronald L, HALLIDAY Christopher I, June 1, 2006: WO/2006/058249 (24 worldwide citation)

This invention relates to an abuse deterrent formulation of an oral dosage form of a therapeutically effective amount of any active drug substance that can be subject to abuse combined with a gel forming polymer, a nasal mucosal irritating surfactant and a flushing agent. Such a dosage form is inten ...


9
Vijai Kumar, David Dixon, Divya Tewari, Dilip B Wadgaonkar: Compositions for deterring abuse of opioid containing dosage forms. Acura Pharmaceuticals, Morgan Lewis & Bockius, January 28, 2014: US08637540 (21 worldwide citation)

This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.


10
Igor Likhotvorik, Joseph J Lisowski: Preparation of opioid analgesics by a one-pot process. Acura Pharmaceuticals, Morgan Lewis & Bockius, September 20, 2005: US06946556 (21 worldwide citation)

A one-pot process for preparing opioid analgesics such as hydrocodone, hydromorphone, and analogues thereof by reacting codeine, morphine, and analogues thereof with hydrogen in a solvent system of benzophenone and neutral solvent in the presence of a metal catalyst followed by oxidation in the pres ...