WO/2009/149188 is referenced by 7 patents.

Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of the p38 MAPK; and wherein the contacting is conducted at a SAPK-modulating concentration that is at a low percentage inhibitory concentration for inhibition of the p38 MAPK by the compound. Also disclosed are derivatives and analogs of pirfenidone, useful for modulating a stress activated protein kinase (SAPK) system.

Title
Compounds and methods for treating inflammatory and fibrotic disorders
Application Number
PCT/US/2009/046136
Publication Number
2009/149188
Application Date
June 3, 2009
Publication Date
December 10, 2009
Inventor
Hu Tao
Bianchi Ivana
Vallese Stefania
Raveglia Luca Francesco Mario
Beigelman Leonid
Ruhrmund Donald
Serebryany Vladimir
Seiwert Scott D
Kossen Karl
Agent
Danek Shelley C
Assignee
Hu Tao
Bianchi Ivana
Vallese Stefania
Raveglia Luca Francesco Mario
Beigelman Leonid
Ruhrmund Donald
Serebryany Vladimir
Seiwert Scott D
Kossen Karl
Intermune
IPC
C07D 213/22
A61K 31/44
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