WO/2009/100110 is referenced by 5 patents.

The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin α5β1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-α5βl antibodies or antigen binding portions thereof described herein.

Title
Alpha 5 - beta 1 antibodies and their uses
Application Number
PCT/US2009/033042
Publication Number
2009/100110
Publication Date
August 13, 2009
Inventor
Yamanaka Mark
Sproul Tim W
Yang Lan
Toy Kristopher
Tanamachi Dawn M
Chen Haibin
Devaux Brigitte
Huang Haichun
Brams Peter
Wickman Grant
Wang Jianying
North Michael Aidan
Li Gang
Jiang Xin
Hu Lowe Dana Dan
Casperson Gerald Fries
Bender Steven Lee
Agent
BRADY James W
Assignee
Yamanaka Mark
Sproul Tim W
Yang Lan
Toy Kristopher
Tanamachi Dawn M
Chen Haibin
Devaux Brigitte
Huang Haichun
Brams Peter
Wickman Grant
Wang Jianying
North Michael Aidan
Li Gang
Jiang Xin
Hu Lowe Dana Dan
Casperson Gerald Fries
Bender Steven Lee
Pfizer
Medarex
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