WO/2008/106058 is referenced by 26 patents.

The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.

Title
Inhibitors of serine proteases
Application Number
PCT/US2008/002395
Publication Number
2008/106058
Application Date
February 20, 2008
Publication Date
September 4, 2008
Inventor
Halas Summer
Cottrell Kevin
Maxwell John
Perni Robert B
Jacobs Dylan
Bethiel Randy Scott
Farmer Luc
Agent
O BRIEN Jonathan P
Assignee
Halas Summer
Cottrell Kevin
Maxwell John
Perni Robert B
Jacobs Dylan
Bethiel Randy Scott
Farmer Luc
Vertex Pharmaceuticals Incorporated
IPC
C07D 498/10
A61P 31/12
A61K 31/407
C07D 487/10
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