WO/2006/089177 is referenced by 40 patents.

The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.

Title
Isoxazole combretastin derivatives for the treatment of disorders
Application Number
PCT/US2006/005761
Publication Number
2006/089177
Application Date
February 16, 2006
Publication Date
August 24, 2006
Inventor
Ying Weiwen
Zhang Mei
Wu Yaming
Foley Kevin
Du Zhenjian
Inoue Takayo
Koya Keizo
Chen Shoujun
Jiang Jun
Li Hao
Borella Christopher
Sun Lijun
Agent
DAVIS Steven G
Assignee
Ying Weiwen
Zhang Mei
Wu Yaming
Foley Kevin
Du Zhenjian
Inoue Takayo
Koya Keizo
Chen Shoujun
Jiang Jun
Li Hao
Borella Christopher
Sun Lijun
Synta Pharmaceuticals
IPC
C07D 413/04
A61P 35/00
A61K 31/42
C07D 261/08
View Original Source