WO/2006/046593 is referenced by 45 patents.

(EN) Disclosed is an excellent LXR modulator. Specifically disclosed is a compound represented by the general formula (I) below or the like. (I) [In the formula, R1 represents a -COR9 (wherein R9 represents an alkyl, optionally substituted alkoxy or optionally substituted amino); R2 represents an H, OH, alkoxy, optionally substituted amino or the like; R3 represents an H, optionally substituted alkyl, cycloalkyl, optionally substituted alkoxy, optionally substituted amino, halogeno or the like; R4 and R5 respectively represent an H, optionally substituted alkyl, halogeno or the like; R6 and R7 respectively represent an H or alkyl; R8 represents a -X2R10 [wherein R10 represents a -COR11 (wherein R11 represents an OH, optionally substituted alkoxy, optionally substituted amino or the like), -SO2R12 (wherein R12 represents an optionally substituted alkyl, optionally substituted amino or the like), tetrazole-5-yl or the like; and X2 represents a single bond, optionally substituted alkylene or the like]; X1 represents an -NH-, -O-, -S- or the like; Y1 represents an optionally substituted phenyl or optionally substituted 5-membered or 6-membered aromatic heterocyclyl; and Y2 represents an optionally substituted aryl, substituted heterocyclyl or the like.](JA) not available

Title
(Ja) 2以上の置換基を有するベンゼン化合物
(En) Benzene compound having 2 or more substituents
Application Number
PCT/JP2005/019676
Publication Number
2006/046593
Application Date
October 26, 2005
Publication Date
May 4, 2006
Inventor
Nakadai Masakazu
Nakai Daisuke
Terasaka Naoki
Oda Kozo
Yamaguchi Takahiro
Tamaki Kazuhiko
Agent
YAGUCHI Toshiaki
Assignee
Nakadai Masakazu
Nakai Daisuke
Terasaka Naoki
Oda Kozo
Yamaguchi Takahiro
Tamaki Kazuhiko
Daiichi Sankyo Company
IPC
C07D 333/24
C07D 307/84
C07D 277/30
C07D 257/04
C07D 239/26
C07D 213/80
C07D 213/79
C07D 213/71
C07D 213/65
C07D 213/55
C07C 65/40
C07C 65/34
C07C 65/30
C07C 65/28
C07C 65/26
C07C 317/46
C07C 317/22
C07C 317/06
C07C 311/25
C07C 311/08
C07C 311/04
C07C 255/57
C07C 235/46
C07C 235/34
C07C 217/80
C07C 205/35
A61K 31/506
A61K 31/455
A61K 31/4418
A61K 31/425
A61K 31/41
A61K 31/381
A61K 31/343
A61K 31/24
A61K 31/216
A61K 31/192
C07C 65/24
View Original Source