WO/2005/081872 is referenced by 23 patents.

The present invention comprises novel compositions and methods for eliciting high immune responses, of great specificity yielding conformationally sensitive antibodies. These antibodies recognize specific epitopes on a wide variety of antigens including but not limited to, amyloid protein, prion protein, P170 glycoprotein. The novel compositions of the invention comprise supramolecular antigenic constructs generally comprising a peptide sequence, covalently attached to pegylated lysine resulting in modified and enhanced peptide presentation. The unique modification methodology of the present invention is applicable to a variety of peptides and can ultimately be employed in therapeutic formulations and vaccines for diseases and disorders such as Alzheimer's disease.

Title
Methods and compositions comprising supramolecular constructs
Application Number
PCT/US2005/005285
Publication Number
2005/081872
Application Date
February 22, 2005
Publication Date
September 9, 2005
Inventor
Hickman David
Greferath Ruth
Nicolau Yves Claude
Agent
PRATT John S
Assignee
Hickman David
Greferath Ruth
Nicolau Yves Claude
Ac Immune
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