WO/2005/079791 is referenced by 8 patents.

Disclosed are compounds of formula (I): wherein Ar1, Ar2, R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.

Title
Thiophene -2- carboxylic acid - (1h - benzimidazol - 2 yl) - amide derivatives and related compounds as inhibitors of the tec kinase itk (interleukin -2- inducible t cell kinase) for the treatment of inflammation, immunological and allergic disorders
Application Number
PCT/US2005/004183
Publication Number
2005/079791
Application Date
February 9, 2005
Publication Date
September 1, 2005
Inventor
Mangette John Edward
Yao Xin
Nemoto Peter Allen
Riether Doris Edith
Zindell Renee M
White Andre
Wang Ji
Takahashi Hidenori
Soleymanzadeh Fariba
Roth Gregory Paul
Pullen Steven S
Mugge Ingo Andreas
Man Chuk Chui
Lo Ho Yin
Li Xiang
Cook Brian Nicholas
Bentzien Joerg Martin
Agent
MORRIS Michael P
Assignee
Mangette John Edward
Yao Xin
Nemoto Peter Allen
Riether Doris Edith
Zindell Renee M
White Andre
Wang Ji
Takahashi Hidenori
Soleymanzadeh Fariba
Roth Gregory Paul
Pullen Steven S
Mugge Ingo Andreas
Man Chuk Chui
Lo Ho Yin
Li Xiang
Cook Brian Nicholas
Bentzien Joerg Martin
Boehringer Ingelheim Pharmaceuticals
IPC
C07D 417/14
C07D 413/14
C07D 409/14
C07D 409/12
A61K 31/4184
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