WO/2005/058941 is referenced by 35 patents.

The present invention is directed to methods of producing conjugates of A&bgr; peptide immunogens with protein/polypeptide carrier molecules, which are useful as immunogens, wherein peptide immunogens are conjugated to protein carriers via activated functional groups on amino acid residues of the carrier or of the optionally attached linker molecule, and wherein any unconjugated reactive functional groups on amino acid residues are inactivated via capping, thus retaining the immunological functionality of the carrier molecule, but reducing the propensity for undesirable reactions that could render the conjugate less safe or effective. Furthermore, the invention also relates to such immunogenic products and immunogenic compositions containing such immunogenic products made by such methods.

Title
A&bgr; immunogenic peptide carrier conjugates and methods of producing same
Application Number
PCT/US2004/044093
Publication Number
2005/058941
Application Date
December 17, 2004
Publication Date
June 30, 2005
Inventor
Prasad A Krishna
Arumugham Rasappa G
Agent
CELLI Rosemarie L
Assignee
Prasad A Krishna
Arumugham Rasappa G
Wyeth
Elan Pharmaceuticals
IPC
C07K 01/00
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