WO/2004/046143 is referenced by 11 patents.

The present invention concerns the compounds of formula (1) (R3)n P(I) N O R1 R2 their N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites, wherein n is 1, 2 or 3; R1 is H, CN, halo, aminoC(=O), C(=O)OH, C1-4-alkyloxyC(=O), C1-4alkylC(='O), mono- or di(C1-4alkyl)aminoC(=O), arylaminoC(=O), N-(aryl)-N-(C1-4alkyl)aminoC(=O), methanimidamidyl, N-hydroxy-methanimidamidyl, mono- or di(C1-4alkyl)methanimidamidyl, Het1 or Het2; R2 is H, C1-10alkyl, C2-10allkenyl, C3-7cycloalkyl, wherein said C1-10alkyl,C2-10alkenyl and C3-7cycloalkyl may be optionally substituted; R3 is nitro, cyano, amino, halo, hydroxy,C1-4alkyloxy, hydroxyC(=O), aminoC(=O), C1-4alkyloxyC(=O), mono- or di(C1-4-alkyl)aminoC(=O), C1-4alkylC(=O), methanimidamidyl, mono- or di(C1-4alkyl)methanimidamidyl, N-hydroxy methanimidamidyl or Het1; for use as a medicine. The invention further relates to a novel subgroup of the compounds of formula (I), and to compositions comprising compounds of formula (I).

Title
Substituted indolepyridinium as anti-infective compounds
Application Number
PCT/EP2003/050837
Publication Number
2004/046143
Application Date
November 14, 2003
Publication Date
June 3, 2004
Inventor
Jochmans Dirk Edward Désiré
Vroey Veronique Corine Paul
de
Bettens Eva
Hertogs Kurt
Canard Maxime Francis Jean Marie Ghislain
Kindermans Natalie Maria Francisca
Vreken Wim
Van de
Kesteleyn Bart Rudolf Romanie
Agent
DAELEMANS Frank
Assignee
Jochmans Dirk Edward Désiré
Vroey Veronique Corine Paul
de
Bettens Eva
Hertogs Kurt
Canard Maxime Francis Jean Marie Ghislain
Kindermans Natalie Maria Francisca
Vreken Wim
Van de
Kesteleyn Bart Rudolf Romanie
Tibotec Pharmaceuticals
IPC
C07D 471/04
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