WO/2002/002781 is referenced by 6 patents.

The present invention relates to the production of bispecific or multispecific, bi- or tetravalent antibodies using recombinant DNA methods and recombinant production methods. The resulting antibody consists of one or two diabody molecules that are heterodimerized by creating a fusion protein with the CL and CH1 immunoglobulin constant domains.

Title
Heterodimeric fusion proteins
Application Number
PCT/EP2001/007557
Publication Number
2002/002781
Application Date
June 29, 2001
Publication Date
January 10, 2002
Inventor
Grooten Johan
Mertens Nico
Agent
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW
Assignee
Grooten Johan
Mertens Nico
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw
IPC
C07K 16/46
C07K 16/00
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