Novel 6-phenylpurine 9-$g(b)-D-ribonucleosides with antineoplastic activity of general formula (I), wherein R?1¿ is H, methyl, fluoro, chloro or alkoxy (C1-C2) group, R?2¿ is H, methyl or fluoro group, and R?3¿ is H, fluoro or methoxy group. Pharmaceutical compositions containing the compounds of the invention as active components are also described. Further the use of compounds of general formula (I) according to Claim 1, or their combinations, for preparing pharmaceutical compositions for the treatment of cancer and leukemia is described.

Title
Novel 6-phenylpurine 9-$g(b)-d-ribonucleosides with antineoplastic activity, their use for preparing pharmaceutical compositions and pharmaceutical preparations containing such compounds
Application Number
PCT/CZ2000/000036
Publication Number
2000/075158
Application Date
May 25, 2000
Publication Date
December 14, 2000
Inventor
Hol&Yacute
Votruba Ivan
Hocek Michal
Agent
GABRIELOVÁ Marta
Assignee
Hol&Yacute
Votruba Ivan
Hocek Michal
Akademie V&Ecaron
Ústav Organické Chemie A Biochemie
IPC
C07H 19/16
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