Peptidyl derivatives of diesters of $g(a)-aminoalkylphosphonic acids, particularly those with proline or related structures, their use in inhibiting serine proteases with chymotrypsin-like, trypsin-like, elastase-like, and dipeptidyl peptidase IV specificity and their roles as anti-inflammatory agents, anticoagulants, anti-tumor agents, and anti-AIDS agents.

Title
Proline phosphonate derivatives
Application Number
PCT/US1995/005345
Publication Number
1995/029691
Application Date
April 28, 1995
Publication Date
November 9, 1995
Inventor
Oleksyszyn Jozef
Boduszek Bogdan
Powers James C
Agent
COLTON Laurence P
Assignee
Georgia Tech Research Corporation
IPC
A61K 38/00
C07K 05/08
C07K 05/06
C07F 09/59
C07F 09/572
C07F 09/40
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