The present invention relates to the preparation and use of liquid formulations of plasma proteins, particularly blood coagulation factors. More specifically, the present invention relates to stable liquid formulations of Factor VIII and Factor IX that can be administered by injection or infusion to provide a constant level of the coagulation factor in the blood.

Title
Methods of production and use of liquid formulations of plasma proteins
Application Number
10/227411
Publication Number
RE38431 (E1)
Application Date
August 26, 2002
Publication Date
February 17, 2004
Inventor
Martin J MacPhee
Montgomery Village
MD, US
Manish P Singh
San Diego
CA, US
John R Taylor Jr
New York
NY, US
Thomas R Jameson
Gaithersburg
MD, US
William N Drohan
Springfield
VA, US
Shirley I Miekka
Gaithersburg
MD, US
Agent
Sterne Kessler Goldstein & Fox PLLC
US
Assignee
The Coalition for Hemophilia B
NY, US
The American National Red Cross
VA, US
IPC
A61K 35/14
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