3896819 is referenced by 76 patents and cites 8 patents.

A drug delivery device for administering a drug at a controlled rate for a prolonged period of time to produce a local or systemic physiological or pharmacological effect is comprised of a wall surrounding a reservoir containing a drug. The reservoir is formed of a drug carrier permeable to the passage of the drug and in which the drug has limited solubility. The drug carrier is liquid and contains both dissolved and undissolved replacement drug. The wall is formed in at least a part of a drug release rate controlling material also permeable to the passage of the drug, but the rate of passage of the drug through the wall is lower than the rate passage of the drug through the drug carrier so that drug release by the wall is the drug release rate controlling step for releasing drug from the drug delivery device.

Title
IUD having a replenishing drug reservoir
Application Number
05/185,208
Publication Number
3896819
Application Date
September 30, 1971
Publication Date
July 29, 1975
Inventor
Alza Corporation
Zaffaroni Alejandro
Agent
Mandell Edward L
Sabatine Paul L
Ciotti Thomas E
IPC
A61m 31/00
A61f 05/46
A61M 31/00
A61M 37/00
A61F 09/00
A61F 06/14
A61F 06/00
A61L 15/58
A61L 15/16
A61K 09/70
A61K 09/00
A61D 07/00
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