3845770 is referenced by 1480 patents and cites 10 patents.

A wall surrounding and forming a compartment for containing a useful composition of matter and having a passageway for dispensing the composition is disclosed. The wall is comprised in at least a part of a material permeable to an external fluid. The composition is soluble in the fluid and exhibits an osmotic pressure gradient against the fluid or the composition has limited solubility and is admixed with an osmotically effective compound soluble in the fluid that exhibits an osmotic pressure gradient against the fluid. In operation, composition is dispensed from the device by fluid permeating into the compartment producing a solution of the soluble composition or a solution of the osmotically effective compound containing the composition, which solution in either operation is released through the passageway to the exterior of the device at a rate controlled by the permeability of the wall and the osmotic pressure gradient across the wall of the device.

Title
Osmatic dispensing device for releasing beneficial agent
Application Number
05/259,469
Publication Number
3845770
Application Date
June 5, 1972
Publication Date
November 5, 1974
Inventor
Higuchi Takeru
Theeuwes Felix
Agent
Benz William H
Mandell Edward L
Sabatine Paul L
Assignee
Alza Corporation
IPC
A61m 31/00
A61F 09/00
A61F 06/14
A61F 06/00
A61K 09/00
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