A percutaneous device for facilitating passage of wires, tubes, and other electrical or fluid conductors through the skin of an animal, in a manner such that the wires, tubes, or other conductors are immobilized with respect to the skin and a fluid and bacterial seal is obtained. The device comprises a generally cylindrical, elongated percutaneous conduit element having a central passageway therethrough and a subcutaneous fenestrated flange disposed in generally surrounding relationship to the conduit element. The subcutaneous flange is provided with a series of holes suitably spaced and sized to facilitate growth of tissue therethrough. The conduit element and the flange are contoured to facilitate the proliferation of the external epidermis down along the outer surfaces of the conduit, out, over and under the surfaces of the subcutaneous flange, through the holes in the flange, and up the passageway in the conduit element. Thus, the epidermis provides, in effect, an exteriorization of the flange and a sphincter around the passageway to immobilize wires, tubes and other electrical or fluid conductors extending through the passageway.