09284371 is referenced by 7 patents and cites 219 patents.

The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.

Title
Methods of producing adalimumab
Application Number
14/920452
Publication Number
9284371 (B2)
Application Date
October 22, 2015
Publication Date
March 15, 2016
Inventor
Thomas Seewoester
Simi Valley
CA, US
Yu Hsiang D Chang
Solana Beach
CA, US
James McIntire
Castro Valley
CA, US
David F Bruton
Enfield
CT, US
Nichole A Roy
Worcester
MA, US
Christof Schulz
Ayer
MA, US
John C Fann
Shrewsbury
MA, US
Joseph G Matuck
Worcester
MA, US
Itzcoatl A Pla
Worcester
MA, US
Agent
Foley Hoag
Assignee
AbbVie
IL, US
IPC
C07K 16/24
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