09101769 is referenced by 2 patents and cites 228 patents.

Methods of enabling locomotor control, postural control, voluntary control of body movements (e.g., in non-weight bearing conditions), and/or autonomic functions in a human subject having spinal cord injury, brain injury, or neurological neuromotor disease. In certain embodiments, the methods involve stimulating the spinal cord of the subject using an epidurally placed electrode array, subjecting the subject to physical training thereby generating proprioceptive and/or supraspinal signals, and optionally administering pharmacological agents to the subject. The combination of stimulation, physical training, and optional pharmacological agents modulate in real time electrophysiological properties of spinal circuits in the subject so they are activated by supraspinal information and/or proprioceptive information derived from the region of the subject where locomotor activity is to be facilitated.

Application Number
13/978035
Publication Number
9101769 (B2)
Application Date
January 3, 2012
Publication Date
August 11, 2015
Inventor
Thomas Anthony Desautels
Pasadena
CA, US
Claudia A Angeli
Louisville
KY, US
Mandheerej S Nandra
Pasadena
CA, US
Yu Chong Tai
Pasadena
CA, US
Jonathan Hodes
Louisville
KY, US
Susan J Harkema
Louisville
KY, US
Joel W Burdick
Pasadena
CA, US
Yury Gerasimenko
Los Angeles
CA, US
Roland R Roy
Playa Vista
CA, US
Victor Reggie Edgerton
Los Angeles
CA, US
Agent
Brian J Novak
Louis C Cullman
K&L Gates
Assignee
University of Louisville Research Foundation
KY, US
California Institute of Technology
CA, US
The Regents of the University of California
CA, US
IPC
A63B 22/02
A63B 69/00
A61H 1/02
A63B 21/00
A61N 1/05
A61N 1/36
A61N 1/18
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