09073988 is referenced by 8 patents and cites 212 patents.

The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.

Title
Fed batch method of making anti-TNF-alpha antibodies
Application Number
14/563993
Publication Number
9073988 (B2)
Application Date
December 8, 2014
Publication Date
July 7, 2015
Inventor
Thomas Seewoester
Simi Valley
CA, US
Yu hsiang D Chang
Solana Beach
CA, US
James McIntire
Castro Valley
CA, US
David F Bruton
Enfield
CT, US
Nichole A Roy
Worcester
MA, US
Christof Schulz
Ayer
MA, US
John C Fann
Shrewsbury
MA, US
Joseph G Matuck
Worcester
MA, US
Itzcoatl A Pla
Worcester
MA, US
Agent
Foley Hoag
Assignee
AbbVie
IL, US
IPC
C12N 5/073
C07K 16/28
C07K 16/00
C07K 16/24
C12N 5/02
C12N 5/00
C12N 5/10
C12N 5/16
C12N 5/07
C12P 21/04
C12P 1/00
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