08999380 is referenced by 21 patents and cites 1385 patents.

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.

Title
Modified polynucleotides for the production of biologics and proteins associated with human disease
Application Number
13/791922
Publication Number
8999380 (B2)
Application Date
March 9, 2013
Publication Date
April 7, 2015
Inventor
Justin Guild
Framingham
MA, US
Jeff Lynn Ellsworth
Lexington
MA, US
Kenechi Ejebe
Cambridge
MA, US
Jason P Schrum
Philadelphia
PA, US
Paul Hatala
Charlestown
MA, US
Kristy M Wood
Cambridge
MA, US
Susan Whoriskey
Belmont
MA, US
Atanu Roy
Stoneham
MA, US
Matthias John
Cambridge
MA, US
Sayda M Elbashir
Cambridge
MA, US
Antonin de Fougerolles
Brookline
MA, US
Tirtha Chakraborty
Medford
MA, US
Stephane Bancel
Cambridge
MA, US
Agent
Jennifer F Bryan
Donna T Ward
DT Ward PC
Assignee
Moderna Therapeutics
MA, US
IPC
A61K 38/00
C12P 21/00
C07K 14/435
C12N 15/52
C12N 9/24
C12N 9/16
C07K 14/005
A61K 38/45
C12P 13/04
C12N 15/87
C12N 9/42
C12N 9/00
C12N 9/10
C12N 9/64
C07K 14/535
C07K 14/505
C07K 14/705
C12N 15/11
A61K 9/127
C12N 9/88
A61K 31/7115
A61K 48/00
C07K 14/62
C07K 14/47
A61K 38/17
C12N 15/85
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