08906367 is referenced by 5 patents and cites 100 patents.

Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes of disease-associated proteins which derive from native endogenous proteins but are prevalent in the body of a patient in a variant form and/or out of their normal physiological context. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of neurological disorders such as Alzheimer's disease are described.

Title
Method of providing disease-specific binding molecules and targets
Application Number
12/522031
Publication Number
8906367 (B2)
Application Date
January 7, 2008
Publication Date
December 9, 2014
Inventor
Jan Grimm
Duebendorf
CH
Kathrin Tissot
Neuried
DE
Marlen Knobloch
Zürich
CH
Christoph Esslinger
Zürich
CH
Christoph Hock
Erlenbach
CH
Roger Nitsch
Zumikon
CH
Assignee
University of Zurich
CH
IPC
A61K 39/00
C07K 16/18
C12P 21/00
C12N 15/00
C07K 16/00
A61K 39/395
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