08708995 is referenced by 27 patents and cites 56 patents.

Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally and radially along the blood vessel. Confirmation that a delivery aperture of the needle lies beyond the EEL may be required before delivering the pharmaceutical agent.

Title
Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation
Application Number
12/790541
Publication Number
8708995 (B2)
Application Date
May 28, 2010
Publication Date
April 29, 2014
Inventor
Robert Cafferata
Santa Rosa
CA, US
Judith Carol Wilber
Oakland
CA, US
Lynn Mateel Barr
Lafayette
CA, US
Kirk Patrick Seward
Dublin
CA, US
Agent
Wilson Sonsini Goodrich & Rosati
Assignee
Mercator MedSystems
CA, US
IPC
A61M 5/00
A61M 31/00
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